{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:13:25Z","timestamp":1792804405794,"version":"4.5.0"},"reference-count":138,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,6,10]],"date-time":"2014-06-10T00:00:00Z","timestamp":1402358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"German Forschungsgemeinschaft","award":["GA2031\/1-1"],"award-info":[{"award-number":["GA2031\/1-1"]}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Gilles de la Tourette syndrome (<jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content>) is a prototypical neuropsychiatric disorder breaking the boundary of disciplinary dualism between neurology and psychiatry. The diagnosis of <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content> is clinical and, in most cases, straightforward. Tics as a hallmark of <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content> are usually easy to recognize and distinguish from other movement disorders as fragmented, repetitive, exaggerated movements resembling normal motor behavior, but appearing out of context. In complex cases, knowledge on additional characteristics and signs as, for example, tic distribution, suggestibility, voluntary tic inhibition, and presence of echo\u2010 or paliphenomena might further aid clinical diagnosis. However, although defining <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content>, tics are rarely the main issue. The presence of comorbidities and coexisting psychopathologies often hampers normal development and negatively affects quality of life. Their recognition and treatment is paramount. Here, we review existing literature and provide a comprehensive update on the multifarious aspects of the movement disorder and neuropsychiatry of <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content>. We also provide a list of associated movement disorders known to occur in <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content> patients and discuss differential diagnoses to be considered in atypical cases. We finally comment on available treatment options.<\/jats:p>","DOI":"10.1002\/mdc3.12043","type":"journal-article","created":{"date-parts":[[2014,6,10]],"date-time":"2014-06-10T06:37:39Z","timestamp":1402382259000},"page":"145-153","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["The Semiology of Tics, Tourette's, and Their Associations"],"prefix":"10.1002","volume":"1","author":[{"given":"Christos","family":"Ganos","sequence":"first","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom"},{"name":"Department of Neurology University Medical Center Hamburg\u2010Eppendorf (UKE) Hamburg Germany"},{"name":"Department of Pediatric and Adult Movement Disorders and Neuropsychiatry Institute of Neurogenetics University of L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"M\u00fcnchau","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Adult Movement Disorders and Neuropsychiatry Institute of Neurogenetics University of L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kailash P.","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,6,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2009.07.010"},{"key":"e_1_2_11_4_1","first-page":"71","volume-title":"Gilles de la Tourette's Syndrome: International Registry","author":"Abuzzahab FS","year":"1976"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2000.tb00346.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.47.1.1"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.152.3.383"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.2009.21.1.13"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.3.425"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f4964"},{"key":"e_1_2_11_11_1","volume-title":"The Psychoanalytic Theory of Neurosis","author":"Fenichel O","year":"1945"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327752jpa4304_1"},{"key":"e_1_2_11_13_1","first-page":"3","article-title":"Psychoanalytic evaluation of tics: a sign and symptom in psychopathology","volume":"279","author":"Mahler MS","year":"1949","journal-title":"Psychoanal Study Child"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01561841"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.4159\/9780674039865"},{"key":"e_1_2_11_16_1","first-page":"105","article-title":"The neurophysiology of Tourette syndrome","volume":"35","author":"Obeso JA","year":"1982","journal-title":"Adv Neurol"},{"key":"e_1_2_11_17_1","volume-title":"Gilles de la Tourette Syndrome","author":"Shapiro AK","year":"1978"},{"key":"e_1_2_11_18_1","first-page":"17","article-title":"Tourette syndrome: history and present status","volume":"35","author":"Shapiro AK","year":"1982","journal-title":"Adv Neurol"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.36.1.1"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2012.11.004"},{"key":"e_1_2_11_21_1","first-page":"237","article-title":"Neurophysiology of tics","volume":"85","author":"Hallett M","year":"2001","journal-title":"Adv Neurol"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23053"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870010103"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(05)70311-X"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870060309"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.2_Part_1.223"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/17588928.2011.604717"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.150.1.98"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.3.359"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6470-1"},{"key":"e_1_2_11_31_1","volume-title":"Gilles de la Tourette Syndrome","author":"Shapiro AK","year":"1988"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(98)00176-0"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)00114-8"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.61.12.1259"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2012-303033"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1901\/jaba.2004.37-417"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1980.01780250029002"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2012.09.009"},{"key":"e_1_2_11_39_1","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198523987.001.0001","volume-title":"Tourette Syndrome: The Facts","author":"Robertson MM","year":"1998"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(01)00219-0"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25103"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03135.x"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700024223"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(05)70326-1"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073808316370"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2011.11.006"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2011.11.004"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-007-1004-6"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2009.09.002"},{"key":"e_1_2_11_50_1","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/DBP.0b013e31823f6933","article-title":"Relationship of obsessive\u2010compulsive disorder to age\u2010related comorbidity in children and adolescents with Tourette syndrome","volume":"33","author":"Wanderer S","year":"2012","journal-title":"J Dev Behav Pediatr"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012959"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(97)02658-9"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3956(97)00028-9"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2010.10.004"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1986.01800120066013"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2272(200001)18:1<33::AID-GEPI3>3.0.CO;2-2"},{"key":"e_1_2_11_57_1","first-page":"684","article-title":"Family study and segregation analysis of Tourette syndrome: evidence for a mixed model of inheritance","volume":"59","author":"Walkup JT","year":"1996","journal-title":"Am J Hum Genet"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2013.11.011"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.3.378"},{"key":"e_1_2_11_60_1","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1097\/00004703-198312000-00012","article-title":"Coincident infantile autism and Tourette syndrome: a case report","volume":"4","author":"Barabas G","year":"1983","journal-title":"J Dev Behav Pediatr"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.141.2.191"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01538324"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.137.10.1267"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320390213"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.148.6.731"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1177\/088307380001500608"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320390212"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00434"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-198703000-00006"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1177\/1362361307070992"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01046229"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073808322666"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2013.08.005"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1017\/S003329179900896X"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.75"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2011.09.034"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5202006"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.10.004"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn223"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2005.03.001"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2007.03.010"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.020693"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700024211"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2007.061"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.09.029"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852900016448"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2013.05.019"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.2.291"},{"key":"e_1_2_11_89_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1600-0404.2003.00228.x"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.02.009"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1097\/YPG.0b013e328015b937"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.107.039909"},{"key":"e_1_2_11_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2008.01.019"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2010.225029"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2013.09.021"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12274"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2013.248"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000086370.10186.7C"},{"key":"e_1_2_11_99_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.160.1.65"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2010.02366.x"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000180957.98702.69"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2006.01687.x"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21599"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199804000-00001"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-012-0278-5"},{"key":"e_1_2_11_106_1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1155\/2013\/732038","article-title":"Health\u2010related quality of life in Gilles de la Tourette syndrome: a decade of research","volume":"27","author":"Cavanna AE","year":"2013","journal-title":"Behav Neurol"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23434"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.neuropsych.11080181"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5754-6"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2001.00147.x"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22900"},{"key":"e_1_2_11_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870130317"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23894"},{"key":"e_1_2_11_114_1","volume-title":"Tics and Related Disorders","author":"Lees AJ","year":"1985"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23484"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1991.00530200104028"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.12001"},{"key":"e_1_2_11_118_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000147298.05983.50"},{"key":"e_1_2_11_119_1","article-title":"Paroxysmal kinesigenic dyskinesia\u2010like symptoms in a patient with Tourette syndrome","volume":"1","author":"Oyama G","year":"2011","journal-title":"Tremor Other Hyperkinet Mov (N Y)"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12056"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-007-0733-0"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050136"},{"key":"e_1_2_11_123_1","first-page":"61","article-title":"Tics associated with other disorders","volume":"99","author":"Jankovic J","year":"2006","journal-title":"Adv Neurol"},{"key":"e_1_2_11_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(05)70315-7"},{"key":"e_1_2_11_125_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22307"},{"key":"e_1_2_11_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2004.02.016"},{"key":"e_1_2_11_127_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2013-305594"},{"key":"e_1_2_11_128_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-011-0163-7"},{"key":"e_1_2_11_129_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1991.01810280040006"},{"key":"e_1_2_11_130_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.7.1067"},{"key":"e_1_2_11_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11526-1"},{"key":"e_1_2_11_132_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200003000-00010"},{"key":"e_1_2_11_133_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v62n0111"},{"key":"e_1_2_11_134_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v62n0908"},{"key":"e_1_2_11_135_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.6.1310"},{"key":"e_1_2_11_136_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870090315"},{"key":"e_1_2_11_137_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.5.605"},{"key":"e_1_2_11_138_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.607"},{"key":"e_1_2_11_139_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-011-0166-4"}],"container-title":["Movement Disorders Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmdc3.12043","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmdc3.12043","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.12043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:43:04Z","timestamp":1760960584000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mdc3.12043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,10]]},"references-count":138,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["10.1002\/mdc3.12043"],"URL":"https:\/\/doi.org\/10.1002\/mdc3.12043","archive":["Portico"],"relation":{},"ISSN":["2330-1619","2330-1619"],"issn-type":[{"value":"2330-1619","type":"print"},{"value":"2330-1619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,10]]},"assertion":[{"value":"2014-03-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-04-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-06-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}