{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:04:23Z","timestamp":1787162663677,"version":"build-2736575974"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T00:00:00Z","timestamp":1412899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Careful, often cumbersome, screening is a fundamental part of\n                    <jats:styled-content style=\"fixed-case\">DBS<\/jats:styled-content>\n                    evaluation in Parkinson's disease (\n                    <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\n                    ). It often involves a brain\n                    <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                    , neuropsychological testing, neurological, surgical, and psychiatric evaluation, and \u201cON\/OFF\u201d motor testing. Given that\n                    <jats:styled-content style=\"fixed-case\">DBS<\/jats:styled-content>\n                    has now been a standard treatment for advanced\n                    <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\n                    , with clinicians\u2019 improved comfort and confidence in screening and referring patients for\n                    <jats:styled-content style=\"fixed-case\">DBS<\/jats:styled-content>\n                    , we wondered whether we can now streamline our lengthy evaluation process. We reviewed all\n                    <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\n                    patients evaluated for\n                    <jats:styled-content style=\"fixed-case\">DBS<\/jats:styled-content>\n                    at our center between 2006 and 2011 and analyzed the reasons for exclusion and for dropping out despite passing the screening process. A total of 223\n                    <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\n                    patients who underwent\n                    <jats:styled-content style=\"fixed-case\">DBS<\/jats:styled-content>\n                    evaluation had complete charting. Only 131 (58.7%) patients were successfully implanted. Sixty\u2010one (27.3%) patients were excluded after screening because of significant cognitive decline (32.7%), early disease with room for medication adjustment (29.5%), behavioral dysfunction (21.3%), suspected secondary parkinsonism or atypical parkinsonism syndrome (13.1%),\n                    <jats:styled-content style=\"fixed-case\">PD,<\/jats:styled-content>\n                    but with poor levodopa response (11.4%), unrealistic goals (9.8%),\n                    <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\n                    with predominant axial symptoms (6.5%), significant comorbidities (6.5%), or abnormal brain imaging (3.2%). In addition, 31 (13.9%) patients were cleared for surgery, but either chose not have it (18 patients), were lost to follow\u2010up (12 patients), or were denied by medical insurance (1 patient). Through careful screening, a significant percentage of surgical candidates continue to be identified as less suitable because of a variety of reasons. This underscores the continued need for a comprehensive, multidisciplinary screening process.\n                  <\/jats:p>","DOI":"10.1002\/mdc3.12090","type":"journal-article","created":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T09:41:55Z","timestamp":1412934115000},"page":"336-341","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Comprehensive, Multidisciplinary\n                    <scp>Deep Brain Stimulation<\/scp>\n                    Screening for Parkinson Patients: No Room for \u201cShort Cuts\u201d"],"prefix":"10.1002","volume":"1","author":[{"given":"Hesham","family":"Abboud","sequence":"first","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"},{"name":"Neurology Department Faculty of Medicine Alexandria University Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja","family":"Mehanna","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Machado","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anwar","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Gostkowski","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Cooper","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilia","family":"Itin","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Sweeney","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayur","family":"Pandya","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Kubu","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darlene","family":"Floden","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Ford","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert H.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Neurological Institute Cleveland Clinic Cleveland Ohio 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