{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T01:38:27Z","timestamp":1780623507221,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T00:00:00Z","timestamp":1450915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007819","name":"Allergan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2016,3]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Waking up from sleep more than once to pass urine, known as nocturia, is an important nonmotor symptom in Parkinson's disease (\n PD<\/jats:styled-content>\n ). Very little is known about the cause for nocturia. The aim of this work was to evaluate lower urinary tract (\n LUT<\/jats:styled-content>\n ) symptoms in patients with\n PD<\/jats:styled-content>\n reporting nocturia using standardized validated questionnaires and bladder diaries and to assess the impact of nocturia on quality of life and sleep.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Twenty\u2010three consecutive patients with\n PD<\/jats:styled-content>\n (17 males, 6 females; mean age: 68.5 years; range, 50\u201385) referred to a specialist uro\u2010neurology clinic reporting nocturia according to the International Continence Society definition were included. Patients measured their daily fluid intake, urinary output per void, and recorded these with the timing of voids on a 3\u2010day bladder diary. Standardized questionnaires were used to assess\n LUT<\/jats:styled-content>\n symptoms (Urinary Symptom Profile, International Prostate Symptom Score, and Qualiveen Short Form) and sleep quality (Parkinson's Disease Sleep Scale).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Mean duration of\n PD<\/jats:styled-content>\n was 10.1 years, and mean severity on H & Y scale was 3.0 (range, 1.0\u20135.0). Median duration of\n LUT<\/jats:styled-content>\n symptoms was 6.0 years. Mean night\u2010time urinary frequency was 3.5 (range, 1.0\u20137.3), and mean nocturnal maximum voided volume was 242 mL. Mean Nocturnal Polyuria Index (\n NP<\/jats:styled-content>\n i) was 0.4 (range, 0.13\u20130.75), and 13 patients (56.5%) had nocturnal polyuria (\n NP<\/jats:styled-content>\n i > 0.33). Patients with nocturnal polyuria reported more\u2010severe\n LUT<\/jats:styled-content>\n symptoms that impacted quality of life and sleep.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n In this preliminary study, nocturnal polyuria seems to be common in patients with\n PD<\/jats:styled-content>\n reporting nocturia and appears to affect quality of life and sleep, though this was not statistically significant. The bladder diary is an essential tool in the assessment of nocturia in patients with\n PD<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/mdc3.12279","type":"journal-article","created":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T08:55:48Z","timestamp":1450947348000},"page":"168-172","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Nocturia in Patients With Parkinson's Disease"],"prefix":"10.1002","volume":"3","author":[{"given":"Matthew","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Uro\u2010Neurology The National Hospital for Neurology and Neurosurgery and UCL Institute of Neurology London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jai","family":"Seth","sequence":"additional","affiliation":[{"name":"Department of Uro\u2010Neurology The National Hospital for Neurology and Neurosurgery and UCL Institute of Neurology London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Batla","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"Hofereiter","sequence":"additional","affiliation":[{"name":"Department of Uro\u2010Neurology The National Hospital for Neurology and Neurosurgery and UCL Institute of Neurology London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kailash P.","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalesh N.","family":"Panicker","sequence":"additional","affiliation":[{"name":"Department of Uro\u2010Neurology The National Hospital for Neurology and Neurosurgery and UCL Institute of Neurology London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20844"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.21125"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.07.004"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20867"},{"key":"e_1_2_7_6_1","first-page":"20","article-title":"Lower urinary tract dysfunction in Parkinson's disease and multiple system atrophy","volume":"2","author":"Batla A","year":"2012","journal-title":"Lead Opin Urol"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1566-0702(01)00295-8"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22519"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","first-page":"878","DOI":"10.3760\/cma.j.issn.0366-6999.20132695","article-title":"Urodynamic analysis and treatment of male Parkinson's disease patients with voiding dysfunction","volume":"127","author":"Xue P","year":"2014","journal-title":"Chin Med J"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10175.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10053"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)00312-5"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.11.100"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36966-5"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(93)90332-5"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)35872-X"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)35874-3"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.08.016"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.73.6.629"},{"key":"e_1_2_7_20_1","unstructured":"Urinary incontinence: the management of urinary incontinence in women. 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