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We describe, for the first time, the treatment of <jats:styled-content style=\"fixed-case\">TD<\/jats:styled-content>s in U.S. children and adults in the outpatient setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from the 2003\u20132010 National Ambulatory Medical Care Survey and the National Hospital Ambulatory Care Survey were used. Descriptive statistics for modality of treatment and class of pharmacological medications were reported by patient and visit characteristics. Separate multivariable logistic regression models were used to examine associations between patient and visit characteristics and classes of medications prescribed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One third (n = 99) of the sample did not receive any psychiatric or psychological treatment. Nearly two\u2010thirds received a psychotropic medication. The most common class of medication was alpha\u20102 agonists (25%), followed by stimulants (23%), serotonin\u2010reuptake inhibitors (<jats:styled-content style=\"fixed-case\">SRI<\/jats:styled-content>s) (19%), atypical antipsychotics (18%), anxiolytics (14%), anticonvulsants (11%), and typical antipsychotics (8%). Comorbid disorders and chronicity of problems were significantly associated with the receipt of certain classes of medications. Relatively few patients (18%) received psychotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>If the decision is made to treat tic disorders, the choice of medication is dependent on the primary complaints, severity, chronicity, and the presence of comorbid psychiatric disorders. In general, comorbid externalizing, anxiety and mood disorders appear to influence treatment decisions in addition to <jats:styled-content style=\"fixed-case\">TD<\/jats:styled-content>s.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.12472","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T10:11:43Z","timestamp":1484302303000},"page":"559-567","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Outpatient Treatment of Tic Disorders Among Children and Adults"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0288-5538","authenticated-orcid":false,"given":"Joseph L.","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Health Policy and Management College of Public Health University of South Florida Tampa Florida 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