{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T10:27:03Z","timestamp":1781260023093,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,10,8]],"date-time":"2017-10-08T00:00:00Z","timestamp":1507420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006518","name":"University of Nebraska Medical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006518","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Orthostatic Tremor (<jats:styled-content style=\"fixed-case\">OT<\/jats:styled-content>) is characterized by the presence of a sensation of instability while standing, associated with high frequency (13\u201318 Hz) lower extremity tremor. Diagnosis is confirmed with surface electromyography (<jats:styled-content style=\"fixed-case\">EMG<\/jats:styled-content>). An accurate screening tool that could be used in the routine clinical setting, without any specialized equipment, would be useful in earlier detection of <jats:styled-content style=\"fixed-case\">OT<\/jats:styled-content> and judicial use of additional testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study was to evaluate <jats:styled-content style=\"fixed-case\">OT<\/jats:styled-content> diagnostic test characteristics at bedside using <jats:styled-content style=\"fixed-case\">iP<\/jats:styled-content>hone's built\u2010in accelerometer and available applications for tremor recordings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We obtained recordings using <jats:styled-content style=\"fixed-case\">iP<\/jats:styled-content>hones (Model 5, 5s, and 6) and free Applications (\u201cLiftPulse\u201d by LiftLabs [App1] and \u201c<jats:styled-content style=\"fixed-case\">iS<\/jats:styled-content>eismometer\u201d by ObjectGraph <jats:styled-content style=\"fixed-case\">LLC<\/jats:styled-content> [App2]) at default settings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>24 <jats:styled-content style=\"fixed-case\">EMG<\/jats:styled-content>\u2010confirmed <jats:styled-content style=\"fixed-case\">OT<\/jats:styled-content> subjects (mostly females, 22\/24) and 15 age\u2010matched controls (mostly males, 11\/15) were evaluated. App1 detected <jats:styled-content style=\"fixed-case\">OT<\/jats:styled-content> range tremor in 22\/24 patients and none of the controls. (Sensitivity = 92%, Specificity = 100%, <jats:styled-content style=\"fixed-case\">NPV<\/jats:styled-content> = 88%). App2 detected <jats:styled-content style=\"fixed-case\">OT<\/jats:styled-content> range tremor in 21\/24 patients and in 1\/13 controls (Sensitivity = 88%, Specificity = 92%, <jats:styled-content style=\"fixed-case\">NPV<\/jats:styled-content> = 80%). When combined, 24\/24 patients and 1\/13 controls had <jats:styled-content style=\"fixed-case\">OT<\/jats:styled-content> range tremor (Sensitivity = 100%, Specificity = 92%, <jats:styled-content style=\"fixed-case\">NPV<\/jats:styled-content> = 100%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Smartphone apps that use the built\u2010in accelerometer provide a simple, accurate and inexpensive bedside screening diagnostic tool for patients with <jats:styled-content style=\"fixed-case\">OT<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.12547","type":"journal-article","created":{"date-parts":[[2017,9,9]],"date-time":"2017-09-09T11:42:34Z","timestamp":1504957354000},"page":"852-857","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Smartphone Apps Provide a Simple, Accurate Bedside Screening Tool for Orthostatic Tremor"],"prefix":"10.1002","volume":"4","author":[{"given":"Danish","family":"Bhatti","sequence":"first","affiliation":[{"name":"Department of Neurological Sciences University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5108-3366","authenticated-orcid":false,"given":"Rebecca","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Hellman","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Penke","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M","family":"Bertoni","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Torres\u2010Russotto","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,8]]},"reference":[{"issue":"3","key":"e_1_2_7_2_1","first-page":"2","article-title":"Consensus statement of the Movement Disorder Society on Tremor","volume":"13","author":"Deuschl G","year":"1998","journal-title":"Mov 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