{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T15:13:23Z","timestamp":1792250003517,"version":"4.4.0"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,23]],"date-time":"2017-11-23T00:00:00Z","timestamp":1511395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"InSightec"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2018,1]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The Fahn\u2010Tolosa\u2010Marin Clinical Rating Scale for Tremor (FTM<\/jats:styled-content>) has been used in large trials for essential tremor (ET<\/jats:styled-content>), but its anchors for ratings from 0 to 4 of upper limb tremor are probably too low for patients with severe tremor (tremor amplitude >4 cm; grade 4). The Essential Tremor Rating Assessment Scale (TETRAS<\/jats:styled-content>) is a validated clinical scale designed specifically for the assessment of ET<\/jats:styled-content> severity. TETRAS<\/jats:styled-content> has anchors that span a larger range of tremor amplitudes (>20 cm = grade 4), making it more suitable for assessing patients with severe ET<\/jats:styled-content>. However, there is no direct comparison of these scales in any clinical trial.<\/jats:p><\/jats:sec>Methods<\/jats:title>Upper limb postural and kinetic tremor items from both scales were compared using blinded, video\u2010recorded examinations of patients with moderate\u2010to\u2010severe ET<\/jats:styled-content> who participated in a trial of focused ultrasound thalamotomy.<\/jats:p><\/jats:sec>Results<\/jats:title>FTM<\/jats:styled-content> ratings of postural and kinetic tremor correlated strongly with those of TETRAS<\/jats:styled-content>. However, FTM<\/jats:styled-content> exhibited a ceiling effect for severe tremor. Rest tremor, exclusive to FTM<\/jats:styled-content>, correlated poorly with postural and kinetic tremor and had very poor test\u2010retest reliability. In contrast, wing\u2010beating postural tremor, exclusive to TETRAS<\/jats:styled-content>, exhibited excellent test\u2010retest reliability and a strong correlation with kinetic and limbs\u2010extended\u2010forward postural tremor. Test\u2010retest reliabilities of the other TETRAS<\/jats:styled-content> and FTM<\/jats:styled-content> ratings were excellent, and both scales had good sensitivity to treatment effect.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>TETRAS<\/jats:styled-content> has 2 main advantages over FTM<\/jats:styled-content> in the assessment of tremor severity: (1) the absence of a ceiling effect in patients with severe ET<\/jats:styled-content>, and (2) the inclusion of wing\u2010beating tremor.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.12560","type":"journal-article","created":{"date-parts":[[2017,10,8]],"date-time":"2017-10-08T21:56:38Z","timestamp":1507499798000},"page":"60-65","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Comparison of the Fahn\u2010Tolosa\u2010Marin Clinical Rating Scale and the Essential Tremor Rating Assessment Scale"],"prefix":"10.1002","volume":"5","author":[{"given":"William","family":"Ondo","sequence":"first","affiliation":[{"name":"Department of Neurology Methodist Neurological Institute Houston TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Hashem","sequence":"additional","affiliation":[{"name":"Department of Neurology Methodist Neurological Institute Houston TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"LeWitt","sequence":"additional","affiliation":[{"name":"Department of Neurology Henry Ford Hospital and Wayne State University West Bloomfield MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Pahwa","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Kansas Kansas City KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludy","family":"Shih","sequence":"additional","affiliation":[{"name":"Parkinson's Disease and Movement Disorders Center Beth Israel Deaconess Medical Center Harvard Medical School Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Tarsy","sequence":"additional","affiliation":[{"name":"Parkinson's Disease and Movement Disorders Center Beth Israel Deaconess Medical Center Harvard Medical School Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Zesiewicz","sequence":"additional","affiliation":[{"name":"Department of Neurology The University of South Florida Tampa FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodger","family":"Elble","sequence":"additional","affiliation":[{"name":"Department of Neurology Southern Illinois University School of Medicine Springfield IL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,23]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"271","volume-title":"Parkinson's Disease and Movement Disorders","author":"Fahn S","year":"1993"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25162"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.29245\/2572.942X\/2016\/4.1038"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21412"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25648"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.5334\/tohm.320","article-title":"Using portable transducers to measure tremor severity [serial online]","volume":"6","author":"Elble RJ","year":"2016","journal-title":"Tremor Other Hyperkinet Mov (N Y)"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1600159"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.12012"}],"container-title":["Movement Disorders Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmdc3.12560","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.12560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:13:05Z","timestamp":1760951585000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mdc3.12560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,23]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1002\/mdc3.12560"],"URL":"https:\/\/doi.org\/10.1002\/mdc3.12560","archive":["Portico"],"relation":{},"ISSN":["2330-1619","2330-1619"],"issn-type":[{"value":"2330-1619","type":"print"},{"value":"2330-1619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,23]]},"assertion":[{"value":"2017-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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