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The International Parkinson and Movement Disorder Society (<jats:styled-content style=\"fixed-case\">MDS<\/jats:styled-content>) commissioned the assessment of the clinimetric properties of motor rating scales in <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> to make recommendations regarding their use, following previously established standardized criteria. After a systematic literature search, a total of 6 rating scales assessing motor symptoms and signs in <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> were included for review. Performance testing (reviewed elsewhere) and quantitative motor rating methods were excluded. Only the Unified Huntington's Disease Rating Scale\u2010Total Motor Score (<jats:styled-content style=\"fixed-case\">UHDRS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TMS<\/jats:styled-content>) was classified as \u201crecommended\u201d for assessing the severity of motor signs in <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>. The following scales were classified as \u201csuggested\u201d: Abnormal Involuntary Movement Scale, the <jats:styled-content style=\"fixed-case\">UHDRS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TMS<\/jats:styled-content>4, the Quantified Neurological Examination, and the Marsden and Quinn Chorea Severity Scale. The committee also concluded that further assessment of existing rating scales, including the <jats:styled-content style=\"fixed-case\">UHDRS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TMS<\/jats:styled-content>, is necessary to determine sensitivity to change and to screening for the presence of motor signs specific to <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>. There is also a need to develop a motor rating scale to be used in positive gene carriers with subtle but not definite motor signs.<\/jats:p>","DOI":"10.1002\/mdc3.12571","type":"journal-article","created":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T06:50:09Z","timestamp":1511765409000},"page":"111-117","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Rating Scales for Motor Symptoms and Signs in Huntington's Disease: Critique and Recommendations"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6973-7479","authenticated-orcid":false,"given":"Tiago A.","family":"Mestre","sequence":"first","affiliation":[{"name":"Division of Neurology Department of Medicine Parkinson's Disease and Movement Disorders Center The Ottawa Hospital Research Institute University of Ottawa Brain and Mind Institute Ottawa Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jo\u00e3o","family":"Forjaz","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics National School of Public Health Carlos III Institute of Health and La Red de Investigaci\u00f3n en Servicios de Salud en Enfermedades Cr\u00f3nicas (REDISSEC) Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0671-0516","authenticated-orcid":false,"given":"Philipp","family":"Mahlknecht","sequence":"additional","affiliation":[{"name":"Department of Neurology Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Movement Disorders Unit Neurology Service Internal Medicine Department The Federal University of Minas Gerais Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim J.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Neurology and Clinical Pharmacology University of Lisbon Institute of Molecular Medicine Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Reilmann","sequence":"additional","affiliation":[{"name":"George\u2010Huntington\u2010Institute Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Sampaio","sequence":"additional","affiliation":[{"name":"CHDI Foundation\/CHDI Management Princeton New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher G.","family":"Goetz","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Cubo","sequence":"additional","affiliation":[{"name":"National Center of Epidemiology and Centro de Investigaci\u00f3n Biomedica en Red de Enfermedades Neurodegenerativas (CIBERNED) Carlos III Institute of Health Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Martinez\u2010Martin","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital Universit\u00e1rio Hermanos Yag\u00fce Burgos Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn T.","family":"Stebbins","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Members of the Movement Disorder Society Committee on Rating Scales Development","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70238-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26011"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21333"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870110204"},{"key":"e_1_2_8_6_1","unstructured":"Huntington Study Group.Unified Huntington's Disease Rating Scale (UHDRS). 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