{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T12:23:31Z","timestamp":1778502211117,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,31]],"date-time":"2021-01-31T00:00:00Z","timestamp":1612051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Bone health and fracture risk reduction are increasingly recognized as important issues in Parkinson's disease (PD). However, the evidence for fracture risk management in atypical parkinsonism (AP) is less clear. Guidance on management of bone health in PD has recently been published.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the outcome of fracture risk assessment in a cohort of patients with AP, compared to a population with idiopathic PD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We did a cross\u2010sectional study of patients with PD or AP who had fracture risk assessed at two tertiary movement disorder centres. Data on fracture risk as assessed using QFracture and FRAX were collected. To assess for the effect of age on fracture risk we compared the risks of PD and AP patients aged \u226470 and &gt;70\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We assessed 71 patients with AP and 267 with PD. Age, sex and body mass index were similar between groups; patients with AP were more likely to have fallen in the previous year. Major osteoporotic fracture risk was greater in patients with AP aged \u226470 compared to PD; no differences between groups were seen in those aged &gt;70\u2009years. 76% of those with AP, and 63% with PD, had an estimated fracture risk indicating bone\u2010sparing treatment, but only 33% of patients with AP were receiving this where it was indicated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is scope for considerable improvement in fracture risk assessment and treatment in atypical parkinsonism, taking into account the worse prognosis of this patient group.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.13146","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T08:59:25Z","timestamp":1610701165000},"page":"385-389","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Fracture Risk Assessment in Atypical Parkinsonian Syndromes"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7797-0756","authenticated-orcid":false,"given":"Christopher","family":"Kobylecki","sequence":"first","affiliation":[{"name":"Department of Neurology, Manchester Centre for Clinical Neurosciences Salford Royal NHS Foundation Trust  Salford United Kingdom"},{"name":"Manchester Academic Health Sciences Centre University of Manchester  Manchester United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Glasse","sequence":"additional","affiliation":[{"name":"Department of Neurology, Manchester Centre for Clinical Neurosciences Salford Royal NHS Foundation Trust  Salford United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jigisha","family":"Amin","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Bristol Medical School University of Bristol  Bristol United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia L.","family":"Gregson","sequence":"additional","affiliation":[{"name":"Musculoskeletal Research Unit, Bristol Medical School University of Bristol  Bristol United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronica","family":"Lyell","sequence":"additional","affiliation":[{"name":"Older People's Unit Royal United Hospitals Bath NHS Foundation Trust  Bath United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0016-1870","authenticated-orcid":false,"given":"Emily J.","family":"Henderson","sequence":"additional","affiliation":[{"name":"Older People's Unit Royal United Hospitals Bath NHS Foundation Trust  Bath United Kingdom"},{"name":"Department of Population Health Sciences, Bristol Medical School University of Bristol  Bristol United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2013-307307"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2019.115173"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afu122"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2005.074070"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2016.05.026"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2012.01.004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e3427"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-007-0543-5"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d3651"},{"key":"e_1_2_7_11_1","unstructured":"National Institute for Health and Care Excellence.Osteoporosis: assessing the risk of fragility fracture: clinical guideline [CG146].2017."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2019.03.021"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn065"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3331"}],"container-title":["Movement Disorders Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.13146","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mdc3.13146","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.13146","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:19:09Z","timestamp":1760955549000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mdc3.13146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,31]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1002\/mdc3.13146"],"URL":"https:\/\/doi.org\/10.1002\/mdc3.13146","archive":["Portico"],"relation":{},"ISSN":["2330-1619","2330-1619"],"issn-type":[{"value":"2330-1619","type":"print"},{"value":"2330-1619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,31]]},"assertion":[{"value":"2020-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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