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Which of the proposed dimensions are preferentially affected in HD, and how these dimensions evolve with disease progression is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The Dimensional Apathy Scale (DAS) separates apathy into Executive, Initiation and Emotional subscales. Using the DAS, we aimed to: 1) Determine the apathy subtypes prevalent in HD; 2) Compare the DAS against a unitary measure of apathy (Apathy Evaluation Scale, AES); 3) Assess the reliability of self\u2010 and observer\u2010ratings; and 4) Determine the relationship between the DAS, and disease burden, total functional capacity (TFC) and the AES.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Fifty pre\u2010manifest, 51 manifest\u2010HD, 87 controls, and 50 HD\u2010observers completed the DAS, AES, and TFC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Manifest\u2010HD participants had the highest levels of apathy across all dimensions (30.4% on Executive subscale, 34.8% on Initiation subscale, and 15.2% on Emotional subscale), relative to pre\u2010manifest and control participants. Self\u2010 and observer\u2010ratings on the DAS did not differ. Hierarchical regressions across the entire gene\u2010expanded sample showed that scores on the Initiation subscale correlated with AES scores; higher Executive subscale scores were related to higher disease burden; and Emotional subscale scores with lower total functional capacity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this first study of the DAS in HD, manifest\u2010HD participants were more apathetic than pre\u2010manifest and control participants across all apathy subtypes. The DAS may be a useful tool for measuring different aspects of apathy in people with HD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.13147","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T08:57:19Z","timestamp":1610701039000},"page":"361-370","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Multidimensional Apathy: The Utility of the Dimensional Apathy Scale in Huntington's Disease"],"prefix":"10.1002","volume":"8","author":[{"given":"Kelly J.","family":"Atkins","sequence":"first","affiliation":[{"name":"School of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie C.","family":"Andrews","sequence":"additional","affiliation":[{"name":"School of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University  Melbourne 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