{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:54:25Z","timestamp":1791197665817,"version":"4.1.0"},"reference-count":67,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,4,4]],"date-time":"2021-04-04T00:00:00Z","timestamp":1617494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,4,4]],"date-time":"2021-04-04T00:00:00Z","timestamp":1617494400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100009683","name":"Parkinson's Queensland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009683","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anxiety is a major complication in Parkinson's disease (PD). Many PD patients experience clinically significant anxiety not meeting Diagnostic and Statistical Manual of Mental Disorders (DSM\u2010IV) anxiety disorder criteria. This atypical anxiety (anxiety disorder not otherwise specified [NOS]) is often under\u2010recognized and its diagnosis is underdeveloped.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to identify the demographic, psychiatric, and clinical characteristics of anxiety disorder NOS in PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional design studied a convenience sample of 184 PD patients without dementia recruited from neurology outpatient clinics. A semi\u2010structured interview using DSM\u2010IV criteria categorized PD patients into current anxiety disorder NOS (n = 28), DSM\u2010IV anxiety disorders (n = 42) or no anxiety (n = 86) groups. Logistic regression modeling identified characteristics associated with the anxiety disorder NOS group compared to DSM\u2010IV anxiety and no anxiety groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The anxiety disorder NOS group was associated with motor complications of PD therapy, episodic, persistent and social anxiety symptoms, depression, non\u2010motor experiences of daily living, poor quality of life, and female sex compared to the no anxiety group. Compared to DSM\u2010IV anxiety, those with anxiety disorder NOS demonstrated greater global cognitive impairment, more severe motor complications of PD therapy, a greater severity and functional impact of dyskinesias, and greater complexity of motor fluctuations. Persistent, episodic, and social anxiety symptoms did not significantly differ between anxiety disorder NOS and DSM\u2010IV anxiety groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that PD\u2010specific symptoms characterize anxiety in a subgroup of PD patients who do not fulfill DSM\u2010IV criteria for anxiety disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.13193","type":"journal-article","created":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T06:08:37Z","timestamp":1615788517000},"page":"571-581","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Defining Atypical Anxiety in Parkinson's Disease"],"prefix":"10.1002","volume":"8","author":[{"given":"Elana J.","family":"Forbes","sequence":"first","affiliation":[{"name":"School of Psychology University of Queensland  Brisbane Queensland Australia"},{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard J.","family":"Byrne","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"},{"name":"Mental Health Service Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"O'Sullivan","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"},{"name":"Department of Neurology Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihyun","family":"Yang","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney","family":"Marsh","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"},{"name":"Asia\u2010Pacific Centre for Neuromodulation University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadeeka N.","family":"Dissanayaka","sequence":"additional","affiliation":[{"name":"School of Psychology University of Queensland  Brisbane Queensland Australia"},{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"},{"name":"Department of Neurology Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.12157"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26643"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20193"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-019-0102-8"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-006434"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2012.06.007"},{"issue":"4","key":"e_1_2_8_8_1","first-page":"201","article-title":"The ups and downs of Parkinson disease: a prospective study of mood and anxiety fluctuations","volume":"17","author":"Richard HI","year":"2004","journal-title":"Cogn Behav Neurol"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-013-0136-4"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2017.09.008"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2006.054759"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2011.02.002"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1993.tb04068.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610215000885"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22611"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2011.01.005"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610215002410"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22340"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.51.6.745"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25919"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000414022"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.148.1.102"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23429"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.17.5.427"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22007"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8341.1959.tb00467.x"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-75373-2_9"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e31823038f2"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/26.5.353"},{"key":"e_1_2_8_30_1","volume-title":"Diagnostic Criteria from DSM\u2010IV\u2010TR","author":"American Psychiatric Association","year":"2000"},{"issue":"20","key":"e_1_2_8_31_1","first-page":"22","article-title":"The Mini\u2010international neuropsychiatric interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM\u2010IV and ICD\u201010","volume":"59","author":"Sheehan DV","year":"1998","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25937"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-59745-530-5_14"},{"issue":"4","key":"e_1_2_8_34_1","first-page":"531","article-title":"Transformation of the independent variables","volume":"4","author":"Box GEP","year":"1962","journal-title":"Dent Tech"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.2011.01185.x"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.318.7183.600a"},{"key":"e_1_2_8_37_1","volume-title":"Using Multivariate Statistics","author":"Tabachnick BG","year":"2007"},{"key":"e_1_2_8_38_1","volume-title":"Essentials of Biostatistics in Public Health","author":"Sullivan LM","year":"2018"},{"key":"e_1_2_8_39_1","volume-title":"Regression Models for Categorical and Limited Dependent Variables","author":"Long JS","year":"1997"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.24041"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21205"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03432.x"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870050210"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.2010.22.4.390"},{"key":"e_1_2_8_45_1","first-page":"2012","article-title":"Neurocognitive correlates of apathy and anxiety in Parkinson's disease","volume":"2012","author":"Bogdanova Y","year":"2012","journal-title":"Parkinsons Dis"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNN.0b013e3181cc8be9"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2012.10.023"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1076\/anec.9.2.77.9543"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2004.00781.x"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.4.2.134"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.73.6.636"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.67.4.492"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23528"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-007-0834-9"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22760"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-013-7085-x"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2012.07.026"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.2009.21.4.413"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22833"},{"issue":"2","key":"e_1_2_8_60_1","first-page":"214","article-title":"Benzodiazepine pharmacology and central nervous system\u2010mediated effects","volume":"13","author":"Griffin CE","year":"2013","journal-title":"Ochsner J"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40734-016-0047-6"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.12740\/APP\/76150"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1159\/000493973"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2016.05.015"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1017\/S104161021700045X"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e31817945c3"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2017.01.001"}],"container-title":["Movement Disorders Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.13193","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mdc3.13193","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.13193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:17:10Z","timestamp":1786630630000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mdc3.13193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,4]]},"references-count":67,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1002\/mdc3.13193"],"URL":"https:\/\/doi.org\/10.1002\/mdc3.13193","archive":["Portico"],"relation":{},"ISSN":["2330-1619","2330-1619"],"issn-type":[{"value":"2330-1619","type":"print"},{"value":"2330-1619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,4]]},"assertion":[{"value":"2020-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}