{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:13:28Z","timestamp":1782184408453,"version":"3.54.5"},"reference-count":107,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T00:00:00Z","timestamp":1627516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A variety of movement disorders can be associated with hypogonadism. Identification of this association may aid in guiding workup and reaching an accurate diagnosis. We conducted a comprehensive and structured search to identify the most common movement disorders associated with hypogonadism. Only Case Reports and Case Series articles were included. Ataxia was the most common movement disorder associated with hypogonadism, including entities such as Gordon\u2010Holmes syndrome, Boucher\u2010Neuh\u00e4user, Marinesco\u2010Sj\u00f6gren and Perrault syndrome. Tremor was also commonly described, particularly with aneuploidies such as Klinefelter syndrome and Jacob's syndrome. Other rare conditions including mitochondrial disorders and Woodhouse\u2010Sakati syndrome are associated with dystonia and parkinsonism and either hypo or hypergonadotropic hypogonadism. We also highlight those entities where a combination of movement disorders is present. Hypogonadism may be more commonly associated with movement disorders than previously appreciated. It is important for the clinician to be aware of this association, as well as accompanying symptoms in order to reach a precise diagnosis.<\/jats:p>","DOI":"10.1002\/mdc3.13308","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T12:48:53Z","timestamp":1626094133000},"page":"997-1011","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Movement Disorders Associated with Hypogonadism"],"prefix":"10.1002","volume":"8","author":[{"given":"Paulina","family":"Gonzalez\u2010Latapi","sequence":"first","affiliation":[{"name":"The Edmond J. Safra Program for Parkinson Disease, Movement Disorder Clinic Toronto Western Hospital, University Health Network  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Sousa","sequence":"additional","affiliation":[{"name":"The Edmond J. Safra Program for Parkinson Disease, Movement Disorder Clinic Toronto Western Hospital, University Health Network  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony E.","family":"Lang","sequence":"additional","affiliation":[{"name":"The Edmond J. Safra Program for Parkinson Disease, Movement Disorder Clinic Toronto Western Hospital, University Health Network  Toronto Ontario Canada"},{"name":"Division of Neurology, Department of Medicine University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,29]]},"reference":[{"issue":"5","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.pcl.2011.07.009","article-title":"Etiology and treatment of hypogonadism in adolescents","volume":"58","author":"Viswanathan V","year":"2011","journal-title":"Pediatr Clin North Am"},{"key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.neubiorev.2016.07.036","article-title":"The organizing actions of adolescent gonadal steroid hormones on brain and behavioral development","volume":"70","author":"Schulz KM","year":"2016","journal-title":"Neurosci Biobehav 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