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From the clinical standpoint, a new classification has completely revised the nosology of tremor syndromes and has re\u2010conceptualized essential tremor as a syndrome rather than a single disease entity, fueling an ongoing enlightened debate. Significant advances have been obtained in terms of instrumental measurement of tremor, remarking on the possibility of developing novel treatment strategies based on tremor characteristics, namely tremor\u2010phase. Moreover, a better understanding of the pathophysiological mechanisms has further led to the suggestion of refining the classification of tremor syndromes according to their driving underpinnings. Finally, surgical options such as deep brain stimulation and focused ultrasound thalamotomy are now part of the therapeutic portfolio for tremor, but several oral drugs, including long\u2010chain alcohols, T\u2010channel blockers, allosteric modulators of potassium channels, and of GABA\u2010A receptors, are currently being tested and hold promise. This review will discuss the key milestones in tremor research of the last 10\u2009years, with a focus on the most common tremor syndromes, namely essential tremor, dystonic tremor, and Parkinsonian tremor.<\/jats:p>","DOI":"10.1002\/mdc3.13418","type":"journal-article","created":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T22:34:46Z","timestamp":1643841286000},"page":"429-435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Milestones in Tremor Research: 10\u2009Years Later"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7800-7419","authenticated-orcid":false,"given":"Roberto","family":"Erro","sequence":"first","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, Neuroscience Section University of Salerno  Baronissi Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5346-0180","authenticated-orcid":false,"given":"Alfonso","family":"Fasano","sequence":"additional","affiliation":[{"name":"Edmond J. 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