{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T18:22:00Z","timestamp":1794075720353,"version":"4.8.0"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:00:00Z","timestamp":1675296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007911","name":"University of California, San Diego","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007911","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Individuals with Huntington's disease (HD) experience motoric, cognitive, and psychiatric dysfunction. These difficulties can cause maladaptive behaviors that can be very distressing to family and caregivers. Capturing these behaviors in clinical and research settings is crucial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To develop and evaluate the psychometric properties of an instrument that is brief, yet comprehensive, in assessing a broad range of behaviors in HD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A pool of 30 items encompassing common behaviors in HD was generated. Items were scored on a 4\u2010point Likert scale ranging from completely disagree to completely agree, with higher scores indicating greater dysfunction. The self\u2010report measure was piloted on a small sample of individuals with HD. Reliability (test\u2013retest, internal consistency) and validity (convergent, discriminant, criterion) were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The HD\u2013Behavioral Questionnaire (HD\u2010BQ) demonstrated evidence for reliability with a test\u2013retest correlation coefficient of <jats:italic>r<\/jats:italic>\u00a0=\u00a00.81 and an internal consistency of 0.96. Validity was established with evidence for good convergent, divergent, and criterion validity. A receiver operating characteristic curve showed that the HD\u2010BQ outperformed a similar commonly used measure in diagnostic capability of behaviors in HD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The HD\u2010BQ, a patient self\u2010report measure, was created to more fully explore behavioral issues that people with HD experience in response to limitations of commonly used instruments in the field. Psychometric evidence supports that the HD\u2010BQ is a valid and reliable instrument for the brief, yet comprehensive, assessment of problematic behaviors in HD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.13661","type":"journal-article","created":{"date-parts":[[2023,1,15]],"date-time":"2023-01-15T23:45:08Z","timestamp":1673826308000},"page":"427-433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Development and Psychometric Properties of a New Brief, Yet Comprehensive, Behavioral Questionnaire for Huntington's Disease"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4351-842X","authenticated-orcid":false,"given":"Shelby","family":"Hughes","sequence":"first","affiliation":[{"name":"Department of Neurosciences University of California, San Diego  La Jolla California USA"},{"name":"San Diego State University\/University of California, San Diego Joint Doctoral Program in 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