{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:39:51Z","timestamp":1761007191801,"version":"build-2065373602"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T00:00:00Z","timestamp":1681257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Multiple System Atrophy (MSA) dysphagia is routinely assessed by the Unified Multiple System Atrophy Rating Scale (UMSARS) part I\u2010item 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the UMSARS part I\u2010item 2 with an ear\/nose\/throat (ENT) expert physician assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed the data of MSA patients who underwent an ENT assessment (nasofibroscopic and radioscopic exam) and an annual UMSARS assessment. Deglutition Handicap Index (DHI) and pulmonary\/nutrition complications were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010five MSA patients were included. The ENT assessment revealed more severe dysphagia compared to the UMSARS part I\u2010item 2 score (<jats:italic>P<\/jats:italic>\u2009=\u20090.003). A higher proportion of patients with impaired protective mechanisms showed severe UMSARS\u2010based dysphagia (<jats:italic>P<\/jats:italic>\u2009=\u20090.005). Patients with choking and oral\/pharyngeal transit defects and nutritional complications were equally distributed across UMSARS part I\u2010item 2 scores. Worse UMSARS part I\u2010item 2 scores had worse DHI scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The UMSARS\u2010based assessment of dysphagia does not capture key aspects of pharyngo\u2010laryngeal dysfunction reflecting swallowing efficiency.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.13734","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T03:29:11Z","timestamp":1680060551000},"page":"974-979","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>UMSARS<\/scp> Versus Laryngoscopy\u2010Based Assessment of Dysphagia"],"prefix":"10.1002","volume":"10","author":[{"given":"Nadia","family":"El Fassi","sequence":"first","affiliation":[{"name":"Department of ENT Hospital of Larrey  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Pavy le Traon","sequence":"additional","affiliation":[{"name":"French Reference Center for Multiple System Atrophy, Neurology Department Toulouse university hospital and Institute of Metabolic and Cardiovascular Diseases INSERM UMR 1297  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuelle","family":"Mouchon","sequence":"additional","affiliation":[{"name":"Department of ENT Hospital of Larrey  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1410-6397","authenticated-orcid":false,"given":"Olivier","family":"Rascol","sequence":"additional","affiliation":[{"name":"Clinical Investigation Center CIC1436, Department of Clinical Pharmacology and Neurosciences, Parkinson Expert Centre and NeuroToul Center of Excellence in Neurodegeneration (COEN) of Toulouse INSERM, University of Toulouse 3, CHU of Toulouse  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2172-7527","authenticated-orcid":false,"given":"Wassilios G.","family":"Meissner","sequence":"additional","affiliation":[{"name":"CHU Bordeaux, Service de Neurologie des Maladies Neurod\u00e9g\u00e9n\u00e9ratives, IMNc  Bordeaux France"},{"name":"Univ. Bordeaux, CNRS, IMN, UMR 5293  Bordeaux France"},{"name":"Dept. Medicine University of Otago, Christchurch, and New Zealand Brain Research Institute  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Foubert\u2010Saumier","sequence":"additional","affiliation":[{"name":"CHU Bordeaux, Service de Neurologie des Maladies Neurod\u00e9g\u00e9n\u00e9ratives, IMNc  Bordeaux France"},{"name":"Univ. Bordeaux, CNRS, IMN, UMR 5293  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohan","family":"Gallois","sequence":"additional","affiliation":[{"name":"Department of ENT Hospital of Larrey  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Tessier","sequence":"additional","affiliation":[{"name":"Service de Pharmacologie M\u00e9dicale et Clinique, Centre de Pharmacovigilance, Facult\u00e9 de M\u00e9decine, de Pharmaco\u00e9pid\u00e9miologie et d'Informations Sur Le M\u00e9dicament CIC INSERM 1436, Centre Hospitalier Universitaire  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6179-4500","authenticated-orcid":false,"given":"Fabienne","family":"Ory\u2010Magne","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital of Toulouse  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginie A.","family":"Woisard","sequence":"additional","affiliation":[{"name":"Department of ENT Hospital of Larrey  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7250-592X","authenticated-orcid":false,"given":"Margherita","family":"Fabbri","sequence":"additional","affiliation":[{"name":"Clinical Investigation Center CIC1436, Department of Clinical Pharmacology and Neurosciences, Parkinson Expert Centre and NeuroToul Center of Excellence in Neurodegeneration (COEN) of Toulouse INSERM, University of Toulouse 3, CHU of Toulouse  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-022-00382-6"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70327-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000008208"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2021.03.027"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940311200710"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29005"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20255"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28854"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2020.104813"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000324625.00404.15"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28220"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-021-10250-2"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13524"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2011.11.006"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2019.02.043"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29215"}],"container-title":["Movement Disorders Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.13734","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T12:03:13Z","timestamp":1760961793000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mdc3.13734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,12]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/mdc3.13734"],"URL":"https:\/\/doi.org\/10.1002\/mdc3.13734","archive":["Portico"],"relation":{},"ISSN":["2330-1619","2330-1619"],"issn-type":[{"type":"print","value":"2330-1619"},{"type":"electronic","value":"2330-1619"}],"subject":[],"published":{"date-parts":[[2023,4,12]]},"assertion":[{"value":"2022-11-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}