{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:41:28Z","timestamp":1761007288914,"version":"build-2065373602"},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:00:00Z","timestamp":1689292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease characterized by widespread accumulation of hyperphosphorylated tau that typically occurs in people who have suffered repetitive head impacts. To date, very few cases have been reported in association football players.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the clinicopathological features of a case of CTE in an 84\u2010year\u2010old former football player who was clinically diagnosed as having dementia with Lewy bodies (DLB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of the patient's primary care and hospital medical records was performed along with a comprehensive neuropathological examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This patient presented at age 84 with symmetrical parkinsonism and cognitive impairment that was exacerbated by prochlorperazine. His condition was rapidly progressive with recurrent falls within 1\u2009year. Other features included headaches, depression, anxiety, suicidal ideation, disturbed sleep and aggression. He received a clinical diagnosis of DLB and died approximately 2\u2009years after the onset of symptoms. A post\u2010mortem examination revealed stage 4 CTE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>While the contemporaneous onset of parkinsonism and cognitive symptoms in the context of possible neuroleptic sensitivity is suggestive of DLB, the additional symptoms of aggressive behavior, depression and suicidality in a former football player are consistent with the neuropathological diagnosis of CTE. This case, which is notable for the late presentation, demonstrates that CTE may masquerade as other dementias and highlights the importance of seeking a history of repetitive head impacts.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.13829","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T08:04:29Z","timestamp":1687939469000},"page":"1414-1418","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Late Presentation of Chronic Traumatic Encephalopathy in a Former Association Football Player"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4360-2680","authenticated-orcid":false,"given":"Patrick W.","family":"Cullinane","sequence":"first","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London  London United Kingdom"},{"name":"Queen Square Brain Bank for Neurological Disorders UCL Queen Square Institute of Neurology  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Wrigley","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London  London United Kingdom"},{"name":"Queen Square Brain Bank for Neurological Disorders UCL Queen Square Institute of Neurology  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teisha Y.","family":"Bradshaw","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Shaw","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London  London United Kingdom"},{"name":"Queen Square Brain Bank for Neurological Disorders UCL Queen Square Institute of Neurology  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Shribman","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2834-2515","authenticated-orcid":false,"given":"Eduardo","family":"de Pablo Fernandez","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London  London United Kingdom"},{"name":"Queen Square Brain Bank for Neurological Disorders UCL Queen Square Institute of Neurology  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6195-6995","authenticated-orcid":false,"given":"Thomas T.","family":"Warner","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London  London United Kingdom"},{"name":"Queen Square Brain Bank for Neurological Disorders UCL Queen Square Institute of Neurology  London United Kingdom"},{"name":"Queen Square Movement Disorders Centre UCL Queen Square Institute of Neurology  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zane","family":"Jaunmuktane","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London  London United Kingdom"},{"name":"Queen Square Brain Bank for Neurological Disorders UCL Queen Square Institute of Neurology  London United Kingdom"},{"name":"Division of Neuropathology, National Hospital for Neurology and Neurosurgery University College London NHS Foundation Trust  London United 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