{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:22:17Z","timestamp":1791829337723,"version":"4.3.4"},"reference-count":49,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:00:00Z","timestamp":1693353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although there is growing recognition of the relevancy of informal caregivers there is scarce information on the contributory factors of caregiver burden in Parkinson's Disease (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To identify the main associated factors to caregivers\u2019 burden in people caring for a person with PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed the data set from a multinational online survey the Parkinson's real\u2010world impact assesSMent (PRISM) focusing on medication use, comorbidities, health\u2010related quality of life, relationship changes and the use of healthcare and supportive care resources by people with PD and their carers. Structured questionnaires including the Parkinson's disease quality of life questionnaire (PDQ\u201039), non\u2010motor symptoms questionnaire (NMSQuest) and the Questionnaire for impulsive\u2010compulsive disorder in Parkinson's disease (QUIP) were applied. Caregiver burden was assessed by the Zarit Burden Interview (ZBI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In a cohort of 245 dyads (patient and respective caregiver), caregivers reported a mild to moderate burden. Carers\u2019 perception of PD impact in partnership, financial burden, hours of care, patient's age, hypersexuality and health\u2010related quality of life (HRQoL) were found to be significant contributory factors to caregiver burden. Taken together these variables explained 66.8% of the variance in the Interpretation of the ZBI total score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Caring for a person with PD entails substantial burden, particularly when the caregiver perceives greater changes in partnership dynamics, dedicates more time to caregiving tasks, has financial burden, and when the patient is older, reports worst HRQoL and has sexual compulsive urges.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.13868","type":"journal-article","created":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T04:09:38Z","timestamp":1692418178000},"page":"1507-1518","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Contributory Factors to Caregiver Burden in Parkinson's Disease"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5822-4539","authenticated-orcid":false,"given":"Gabriela M.","family":"Soares","sequence":"first","affiliation":[{"name":"Faculdade de Medicina Universidade de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3756-2763","authenticated-orcid":false,"given":"Raquel","family":"Bou\u00e7a\u2010Machado","sequence":"additional","affiliation":[{"name":"CNS\u2010Campus Neurol\u00f3gico  Torres Vedras Portugal"},{"name":"Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes, Faculdade de Medicina Universidade de Lisboa  Lisbon Portugal"},{"name":"Laboratory of Clinical Pharmacology and Therapeutics, Faculdade de Medicina Universidade de Lisboa  Lisbon 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