{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T23:01:23Z","timestamp":1771023683520,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T00:00:00Z","timestamp":1701820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The role of deep brain stimulation in the treatment of dystonia has been widely documented. However, there is limited literature on the outcome of lesioning surgery in unilateral dystonia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>We restrospectively reviewed our cases of focal and hemidystonia undergoing unilateral Pallidotomy at our institute to evaluate the short\u2010term and long\u2010term outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent radiofrequency lesioning of GPi for unilateral dystonia between 1999 and 2019 were retrospectively reviewed. All patients were evaluated using the Burke\u2013Fahn\u2013Marsden Dystonia Rating Scale (BFMDRS) and Dystonia Disability Scale (DDS) preoperatively at the short term follow\u2010up (&lt;1\u2009year) and at long\u2010term follow\u2010up (2\u20137.5\u2009years). Video recordings performed at these time points were independently reviewed by a blinded movement disorders specialist.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eleven patients were included for analysis. The preoperative, short\u2010term, and long\u2010term follow\u2010up motor BFMDRS and DDS scores were 15.5 (IQR [interquartile range]: 10.5, 23.75) and 10.5 (IQR: 6.0, 14.5); 3.0 (IQR: 1.0, 6.0, <jats:italic>P<\/jats:italic>\u2009=\u20090.02) and 3.0 (IQR: 3.0, 8.0, <jats:italic>P<\/jats:italic>\u2009=\u20090.016); and 14.25 (IQR: 4.0, 20.0, <jats:italic>P<\/jats:italic>\u2009=\u20090.20) and 10.5 (IQR: 2.0, 15.0, <jats:italic>P<\/jats:italic>\u2009=\u20090.71) respectively. For observers B, the BFMDRS scores at the same time points were 19 (IQR: 12.5, 27.0), 7.5 (IQR: 6.0, 15.0, <jats:italic>P<\/jats:italic>\u2009=\u20090.002), and 21 (IQR: 7.0, 22.0, <jats:italic>P<\/jats:italic>\u2009=\u20090.65) respectively. The improvement was statistically significant for all observations at short\u2010term follow\u2010up but not at long\u2010term follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pallidotomy is effective for hemidystonia or focal dystonia in the short term. Continued benefit was seen in the longer term in some patients, whereas others worsened. Larger studies may be able to explain this in future.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.13912","type":"journal-article","created":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T04:14:05Z","timestamp":1698466445000},"page":"30-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes of Unilateral Pallidotomy in Focal and Hemidystonia Cases: A Single\u2010Blind Cohort Study"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6333-1494","authenticated-orcid":false,"given":"Paresh K.","family":"Doshi","sequence":"first","affiliation":[{"name":"Department of Stereotactic and Functional Neurosurgery Jaslok Hospital and Research Centre  Mumbai 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