{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:04:14Z","timestamp":1782846254197,"version":"3.54.5"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T00:00:00Z","timestamp":1702166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Parkinson's disease (PD) is associated with psychosocial distress that affects patients\u2019 quality of life. The distress thermometer (DT) is an 11\u2010point visual analogue scale that is used as a screening tool for the assessment of psychosocial distress, originally developed for oncological diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To validate the DT for PD and to explore contributing factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The DT scale was administered to 105 people with Parkinson's Disease (PwPD). Along with it, we assessed motor symptoms (Unified Parkinson's Disease Rating Scale part III [UPDRS III], Hoehn and Yahr\u2010stage [H&amp;Y]), non\u2010motor symptoms (Non\u2010motor Symptom Questionnaire [NMSQ]), anxiety and depression (Hospital Anxiety and Depression Scale [HADS], Fear of Progression\u2010Questionnaire Short Form [FOP\u2010Q\u2010SF], Generalized Anxiety Disorder Scale\u20107 [GAD\u20107], 9\u2010question Patient Health Questionnaire [PHQ\u20109]), the feeling of hope (Herth Hope Index [HHI]) and quality of life (Schedule for the Evaluation of Individual Quality of Life [SEIQoL]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>With a cut\u2010off of 4, the DT identified PwPD with distress with a sensitivity of 97% and a specificity of 38%. With this cut\u2010off, the DT will yield false negative results in 1 out of 100 cases. Factor analyses and a random forest regression of the dataset revealed that distress can be predicted by two factors, which we termed \u201canxiety\u201d and \u201cdepression\/resilience\/motor symptoms\u201d.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The DT is an ultra\u2010short and reliable screening tool for distress in PwPD. DT values below 4 rule out distress with a high degree of certainty. Anxiety and depression are important factors in distress but are counterbalanced by the individuals\u2019 psychological resilience.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.13937","type":"journal-article","created":{"date-parts":[[2023,11,25]],"date-time":"2023-11-25T05:54:26Z","timestamp":1700891666000},"page":"257-264","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Validation of the Distress Thermometer as a Screening Tool for Psychosocial Distress and Resilience in Parkinson's Disease"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0870-8105","authenticated-orcid":false,"given":"Nils","family":"Schnalke","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital Carl Gustav Carus Dresden  Dresden Germany"},{"name":"Center for Neurodegenerative Diseases within the Helmholtz Association (DZNE)  Dresden 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