{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:19:32Z","timestamp":1791350372702,"version":"4.3.1"},"reference-count":71,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:00:00Z","timestamp":1715040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013301","name":"Parkinson's Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013301","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Quality of life (QoL) is known to be impaired in people with Parkinson's disease (PwPD). Not surprisingly, a considerable effort of health interventions is aimed at maintaining or improving QoL. Yet, little is known about its determinants from a PwPD perspective to inform person\u2010centered health care interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This systematic review aims to overcome this information gap by synthesizing existing evidence on factors associated with PwPD\u2019 self\u2010perceived QoL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched six electronic databases (MEDLINE, EMBASE, PsycINFO, CINAHL, Web of Science, Cochrane Library) from inception to January 2022 for eligible qualitative studies of QoL in PwPD, supplemented by citation tracking and hand searching. Study quality was assessed using the QualSyst tool. In order to characterize the determinants of QoL in PwPD, we conducted a qualitative meta\u2010synthesis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our analysis revealed a wide range of facilitators and barriers to QoL relating to seven overarching themes: Illness experience, health care, everyday life, social life, identity, spirituality\/religion, and environment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our systematic review reinforces the impact of symptom experience on PwPD's QoL. However, it also highlights the need to consider the non\u2010physical dimensions of PD when assessing patients\u2019 QoL. It is therefore essential that health care professionals acknowledge the psychological, social and spiritual repercussions of PD and endeavor to respond to these concerns through a comprehensive and patient\u2010centered strategy. Further research is needed to gain a deeper understanding of these facets of PD and to formulate successful interventions aimed at improving the QoL of PwPD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.14063","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T00:28:13Z","timestamp":1715128093000},"page":"761-769","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Quality in Quality of Life in Parkinson's Disease: A Qualitative Meta\u2010Synthesis"],"prefix":"10.1002","volume":"11","author":[{"given":"Marlena","family":"van Munster","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital of Marburg  Marburg Germany"},{"name":"Department of International Health Maastricht University, CAPHRI Care and Public Health Research Institute  Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4757-9019","authenticated-orcid":false,"given":"Anna J.","family":"Pedrosa","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital of Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin","family":"K\u00fcnkler","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital of Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Pedrosa","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital of Marburg  Marburg Germany"},{"name":"Centre for Mind, Brain and Behavior Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25945"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.13458"},{"key":"e_1_2_9_4_1","volume-title":"Parkinson Disease: A Public Health Approach. 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