{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:21:01Z","timestamp":1791580861655,"version":"4.3.4"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with Progressive Supranuclear Palsy (PSP) suffer from several neuropsychological impairments. These mainly affect the frontal lobe and subcortical brain structures. However, a scale for the assessment of cognitive and neuropsychiatric disability in PSP is still missing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To create and validate a new scale for cognitive and neuropsychiatric impairment in PSP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Short Cognitive and Neuropsychiatric (ShoCo) scale was developed containing five items (bradyphrenia, apathy, aphasia, dysexecution and disinhibition). Each item can be categorized into 0\u2009=\u2009no deficit, 1\u2009=\u2009mild deficit, 2\u2009=\u2009moderate deficit and 3\u2009=\u2009severe deficit. The total score includes 15 points, 0 meaning no deficit and 15 severe deficits. Cross\u2010sectional and longitudinal data from 201 baseline and 71 follow up patients were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline ShoCo scale results were 5.9\u2009\u00b1\u20092.9. No significant differences between patients with Richardson syndrome (PSP\u2010RS) and variants (vPSP) could be detected in the PSP\u2010ShoCo scale scores (PSP\u2010RS 6.1\u2009\u00b1\u20093.0, n\u2009=\u2009160, vPSP 5.1\u2009\u00b1\u20092.6, n\u2009=\u200941,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.057). The scale showed good correlation with established scores (eg, Montreal cognitive assessment r\u2009=\u2009\u22120.535,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001). The ShoCo scale showed significant annualized change within the PSP\u2010RS patients (baseline 6.2\u2009\u00b1\u20092.9, follow up 6.9\u2009\u00b1\u20093.1, annualized diff. 1.0\u2009\u00b1\u20093.1, n\u2009=\u200957,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.022).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The ShoCo scale seems a promising and valid tool to measure specific neuropsychological disabilities of PSP patients in clinical routine and research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.14348","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T08:53:53Z","timestamp":1737968033000},"page":"764-774","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Short Cognitive and Neuropsychiatric Assessment Scale for Progressive Supranuclear Palsy"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4542-3000","authenticated-orcid":false,"given":"Sonja","family":"Porsche","sequence":"first","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3054-9905","authenticated-orcid":false,"given":"Martin","family":"Klietz","sequence":"additional","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0638-8571","authenticated-orcid":false,"given":"Stephan","family":"Greten","sequence":"additional","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines A.","family":"Piot","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0270-0029","authenticated-orcid":false,"given":"Ida","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover Germany"},{"name":"Department of Neurology LMU University Hospital, LMU Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Wegner","sequence":"additional","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover 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