{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T17:12:51Z","timestamp":1785863571297,"version":"3.56.0"},"reference-count":11,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Essential tremor is the most common hyperkinetic movement disorder. Magnetic resonance imaging\u2013guided focused ultrasound (MRgFUS) has emerged as second\u2010line therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim was to obtain the results of the first 108 patients treated with MRgFUS in Denmark.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were entered in a quality assurance database at baseline and 3, 6, and 12 months. Clinician\u2010 and patient\u2010rated treatment efficacy was evaluated using the Fahn\u2013Marin\u2013Tolosa (FMT) scale and the Patient Global Impression of Change.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 108 persons have currently been treated. Tremor improved by a total mean 6.39 points (95% confidence interval [CI]: 5.01;7.76, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.00001) and 9.63 points (95% CI: 7.60;11.66, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.00001), 10.42 (95% CI: 9.06;11.79, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.00001), and 26.45 (95% CI: 22.46;30.43, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.00001) for FMT parts A, B, and C, respectively, at 3 months. Side effects occurred in 65.7% of patients at 3 months and 33.7% at 12 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings are in line with existing evidence. Questions regarding persistence of gait\u2010 and balance\u2010related side effects remain.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.70012","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T07:50:02Z","timestamp":1739951402000},"page":"922-927","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Magnetic Resonance\u2013Guided Focused Ultrasound Treatment for Essential Tremor: A Single\u2010Center Experience"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4915-7899","authenticated-orcid":false,"given":"Victor S.","family":"Hvingelby","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Aarhus University Hospital  Aarhus Denmark"},{"name":"Center of Experimental Neuroscience, Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Health Clinical Institute, Aarhus University  Aarhus 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