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Actigraphy data were obtained over 14\u2009days and analyzed using nonparametric methods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>DLB patients demonstrated higher rest\u2013activity rhythm fragmentation (<jats:italic>P<\/jats:italic>\u2009=\u20090.002) than controls and lower circadian amplitude (<jats:italic>P<\/jats:italic>\u2009=\u20090.011) than both PD and controls. Instability of rest\u2013activity rhythm was positively correlated with hallucinations (<jats:italic>P<\/jats:italic>\u2009=\u20090.009) and cognitive fluctuations (<jats:italic>P<\/jats:italic>\u2009=\u20090.016) in DLB, and reduced daytime activity correlated with severity of motor parkinsonism (<jats:italic>P<\/jats:italic>\u2009=\u20090.013). No such correlations were observed in PD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Actigraphy detects distinct rest\u2013activity rhythm disruptions in DLB, differentiating it from PD and controls. These measures are associated with the severity of core clinical features in DLB.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mdc3.70052","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T04:46:43Z","timestamp":1743050803000},"page":"1140-1145","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Rest\u2013Activity Disturbances Correlate with Core Features in Dementia with Lewy Bodies"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4967-7372","authenticated-orcid":false,"given":"Jack","family":"Anderson","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health, Central Clinical School The University of Sydney  Sydney New South Wales Australia"},{"name":"Centre for Integrated Research and Understanding of Sleep (CIRUS) Woolcock Institute of Medical Research  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9012-8010","authenticated-orcid":false,"given":"Nicholas K.H.","family":"Chiu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health, Central Clinical School The University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Psychiatry Pamela Youde Nethersole Eastern Hospital  Hong Kong, SAR China"},{"name":"Department of Medicine and Therapeutics, Faculty of Medicine, Margaret K.L. 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