{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T22:02:24Z","timestamp":1775685744572,"version":"3.50.1"},"reference-count":79,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP\u2010126017"],"award-info":[{"award-number":["MOP\u2010126017"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mild behavioral impairment (MBI) is a syndrome characterized by the later\u2010life onset of neuropsychiatric symptoms (NPS) and serves as a potential marker for dementia. In Parkinson's disease (PD), MBI has been associated with worse cognition, cortical atrophy, and altered connectivity. Unlike existing instruments that assess NPS in PD, the MBI Checklist (MBI\u2010C) leverages sustained behavioral changes to identify patients at risk of cognitive impairment and neurodegeneration. The 34\u2010item MBI\u2010C has yet to be validated in PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study assesses the MBI\u2010C's psychometric properties in a multicenter Canadian PD sample and proposes a revised version optimized for PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 406 PD patients from the Canadian Open Parkinson Network were assessed with the MBI\u2010C to investigate its construct validity. Additional evaluations, including the Movement Disorder Society\u2010Unified Parkinson's Disease Rating Scale (MDS\u2010UPDRS), Neuropsychiatric Inventory (NPI), and Montreal Cognitive Assessment (MoCA), were implemented to examine the concurrent and criterion validities of the checklist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The original MBI\u2010C exhibited considerable floor effects (24.9%). Exploratory factor analysis revealed a 5\u2010factor 24\u2010item MBI\u2010C as consistent for PD (Cronbach's \u03b1\u2009=\u20090.856). All intrafactor correlations were statistically significant (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05), and convergent validity was found to be higher than divergent validity. Moreover, the MBI\u2010C demonstrated moderate concurrent validity with the NPI (intraclass correlation coefficient [ICC]: 0.633,\n                      <jats:italic>P\u2009&lt;<\/jats:italic>\n                      \u20090.001). The cutoff score associated with cognitive impairment on the revised instrument was 6|7.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Compared to the original version, the revised MBI\u2010C exhibited enhanced psychometric properties for measuring MBI in PD. It also demonstrated acceptable specificity when related to cognitive impairment. Future psychometric research should focus on capturing the subtlest manifestations of MBI in PD, examining patient\u2010caregiver concordance, and addressing predictive validity for cognitive decline.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70243","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T07:24:46Z","timestamp":1754292286000},"page":"108-119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Mild Behavioral Impairment Checklist for Parkinson's Disease: An Ancillary Instrument in Cognitive Assessment"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1149-8193","authenticated-orcid":false,"given":"Gabriel D.","family":"Pinilla\u2010Monsalve","sequence":"first","affiliation":[{"name":"Centre de recherche de l'Institut universitaire de g\u00e9riatrie de Montr\u00e9al  Montreal Quebec 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