{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T11:40:19Z","timestamp":1775821219468,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:00:00Z","timestamp":1754524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:00:00Z","timestamp":1754524800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dystonia affects an estimated 30% of patients with Parkinson's Disease (PD). While pallidal theta\u2010alpha oscillations (4\u201310\u2009Hz) have been found to characterize primary dystonia compared to beta oscillations (12\u201330\u2009Hz) in PD, the electrophysiology underlying dystonia in PD remains unexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Explore the electrophysiology underlying dystonia in PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Subthalamic nucleus (STN) local field potentials (LFPs) in PD patients with and without dystonia were compared using a bidirectional deep brain stimulation (DBS) device.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fourteen PD patients with bilateral STN\u2010DBS were included, four (28.6%) with lower extremity dystonia. In 3\/7 hemispheres affected by dystonia (42.9%), maximum amplitude LFP activity occurred in the theta\u2010alpha band (4\u201310\u2009Hz). Conversely, all 21 hemispheres not associated with dystonia had maximum STN activity around the beta\u2010band (11.5\u201335\u2009Hz,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.011).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>STN theta\u2010alpha activity in patients with PD may be associated with dystonic symptoms. Although other motor and non\u2010motor features may correlate with STN theta\u2010alpha, this biomarker warrants further investigation in closed\u2010loop DBS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70284","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T09:18:31Z","timestamp":1754558311000},"page":"223-229","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Subthalamic Theta\u2010Alpha Local Field Potentials in\n                    <scp>OFF<\/scp>\n                    \u2010Levodopa Dystonia in Parkinson's Disease"],"prefix":"10.1002","volume":"13","author":[{"given":"Daniel D.","family":"Cummins","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Mount Sinai Health System  New York New York 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