{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T03:14:05Z","timestamp":1790046845114,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000061","name":"Fogarty International Center","doi-asserted-by":"publisher","award":["Award Number D43TW009345"],"award-info":[{"award-number":["Award Number D43TW009345"]}],"id":[{"id":"10.13039\/100000061","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The global prevalence of Parkinson's disease (PD) is estimated to be 315 per 100,000 inhabitants, with variations across regions and depending on the epidemiological methods used. Door\u2010to\u2010door prevalence studies in Andean communities are notably underrepresented in the literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study was to estimate the PD prevalence in Jauja.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional community\u2010based door\u2010to\u2010door prevalence study was conducted from April 2018 to September 2019. We used a Spanish version of the 9\u2010item screening questionnaire (9\u2010item SQ). Trained interviewers conducted face\u2010to\u2010face screening surveys. Participants presenting \u201csuspected parkinsonism\u201d underwent further neurological assessment. PD cases responded to the LARGE\u2010PD questionnaire and \u201cpesticide exposure questionnaire.\u201d We calculated the crude prevalence, gender\u2010 and age\u2010specific rates, and age\u2010adjusted rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 2527 eligible individuals, 1960 completed the screening survey. Of these, 563 were selected for neurological assessment, and 337 underwent neurological examination. PD was confirmed in 21 individuals, 16 of whom were identified using the 9\u2010item SQ with a crude prevalence of 816\/100,000. We observed higher rates of PD in older age groups and in males compared to females (1.6 vs. 0.3%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05). The age\u2010standardized prevalence was 566\/100,000 (95% confidence interval [CI]: 496.6\u2013635.2). Among PD cases, the most common environmental exposures were living near farming fields and pesticide exposure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The observed prevalence of PD in this town in the central highlands of Peru aligns with previous reports, with notably higher rates among individuals over the age of 80. Further prospective studies are warranted to investigate the potential influence of environmental factors on PD prevalence in this region.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70354","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:02:33Z","timestamp":1758276153000},"page":"692-701","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence of Parkinson's Disease in a Town of the Central Highlands of Peru: A Population\u2010Based Study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1562-3062","authenticated-orcid":false,"given":"Elison","family":"Sarapura\u2010Castro","sequence":"first","affiliation":[{"name":"Neurogenetics Working Group Universidad Cientifica del Sur  Lima Peru"},{"name":"Northern Pacific Global Health Research Program, NIH  Bethesda Maryland USA"},{"name":"Neurogenetics Research Center 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del Sur  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3911-9776","authenticated-orcid":false,"given":"Andrea","family":"Rivera\u2010Valdivia","sequence":"additional","affiliation":[{"name":"Northern Pacific Global Health Research Program, NIH  Bethesda Maryland USA"},{"name":"Neurogenetics Research Center Instituto Nacional de Ciencias Neurologicas  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3770-0476","authenticated-orcid":false,"given":"Miguel","family":"Inca\u2010Martinez","sequence":"additional","affiliation":[{"name":"Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3098-0981","authenticated-orcid":false,"given":"Maryenela","family":"Illanes\u2010Manrique","sequence":"additional","affiliation":[{"name":"Neurogenetics 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