{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:07:44Z","timestamp":1790230064022,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:00:00Z","timestamp":1760659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:00:00Z","timestamp":1760659200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,4]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Heterogenous, small cohorts, and co\u2010occurrence of pain and psychiatric burden complicate understanding of sleep in dystonia.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To investigate sleep concerns in cervical dystonia (CD).<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Longitudinal data from CD\u2010PROBE on subjects who were toxin\u2010na\u00efve, new to practice, or without injections for at least 16\u2009weeks were analyzed. Cervical Dystonia Impact Profile captured sleep disturbances. Impact of OnabotulinumtoxinA on sleep was assessed using multilevel mixed models, controlling for demographics, dystonia severity, mood, and pain.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n 56% (n\u2009=\u20091037) reported concerns with sleep initiation, restfulness, maintenance, and total time. Initial injection led to a clear improvement in sleep. (\n P<\/jats:italic>\n \u2009<\u20090.001) Motor severity (\u03b2: 0.20,\n P<\/jats:italic>\n \u2009<\u20090.001), mood (\u03b2: 0.36,\n P<\/jats:italic>\n \u2009<\u20090.001), and pain (\u03b2: 0.58,\n P<\/jats:italic>\n \u2009<\u20090.001) predicted sleep improvement (n\u2009=\u2009502) over three OnabotulinumtoxinA cycles.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Sleep concerns are common in CD, with initial and subsequent improvement with OnabotulinumtoxinA. Impact of mood and pain on sleep highlights the importance of non\u2010motor features.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/mdc3.70393","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T09:56:32Z","timestamp":1760694992000},"page":"1044-1049","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Investigating Sleep Concerns in Cervical Dystonia"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8807-6672","authenticated-orcid":false,"given":"Abhimanyu","family":"Mahajan","sequence":"first","affiliation":[{"name":"James J. and Joan A. Gardner Family Center For Parkinson's Disease and Movement Disorders University of Cincinnati Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0882-7689","authenticated-orcid":false,"given":"David Andr\u00e9s","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Division of Movement Disorders, Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Comella","sequence":"additional","affiliation":[{"name":"Division of Movement Disorders, Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29387"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2020-325193"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.04.004"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.12459"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsx088"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-10802-y"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-11-140"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.13655"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26534"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-012-0887-7"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000142962.11881.26"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/dyst.2025.14545"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins13090647"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13760-025-02742-x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1115482"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2014.01.004"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2023.105792"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000249310.25427.f2"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25579"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-6-58"}],"container-title":["Movement Disorders Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.70393","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mdc3.70393","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.70393","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T06:36:21Z","timestamp":1776062181000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mdc3.70393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,17]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/mdc3.70393"],"URL":"https:\/\/doi.org\/10.1002\/mdc3.70393","archive":["Portico"],"relation":{},"ISSN":["2330-1619","2330-1619"],"issn-type":[{"value":"2330-1619","type":"print"},{"value":"2330-1619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,17]]},"assertion":[{"value":"2025-07-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}