{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:57:14Z","timestamp":1790287034297,"version":"4.1.0"},"reference-count":344,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To provide an updated overview of existing MDS\u2010recommended COAs in PD and to identify specific constructs requiring revision or further validation to inform current clinical practice and research.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Scientific Evaluation Committee of the Movement Disorder Society COA program commissioned a position paper on the current state of COAs\u2019 recommendations. A panel of experts conducted a two\u2010step review: first, extracting data from previous MDS publications of rating scales on COAs appraisals using a standardized template; second, conducting a scoping review up to April 2025 to identify new COAs or updated validation data on motor and non\u2010motor constructs in PD. All study designs were considered.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 19 PD constructs identified, anxiety, apathy, anhedonia, dysautonomia, and pain had significant developments, including new COA development and further validation, making them priorities for revision. Recent reviews show that constructs like medication adherence and psychosis were sufficiently addressed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This review identifies key symptom areas where COA critique and recommendations need to be updated to reflect advances in the field and improve assessment accuracy in clinical and research settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70410","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T18:20:18Z","timestamp":1761762018000},"page":"1124-1146","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs"],"prefix":"10.1002","volume":"13","author":[{"given":"Evita","family":"Papathoma","sequence":"first","affiliation":[{"name":"Department of Clinical Neuroscience Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Neurology Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3790-0398","authenticated-orcid":false,"given":"Panagiota","family":"Tsitsi","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Neurology Onze\u2010Lieve\u2010Vrouw Hospital  Aalst Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9671-0212","authenticated-orcid":false,"given":"Nirosen","family":"Vijiaratnam","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neuroscience University College London Queen Square Institute of Neurology  London UK"},{"name":"Clinical Research Centre for Movement Disorders and Gait, Kingston Centre Parkinson's Foundation Centre of Excellence, Monash Health  Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Aquino","sequence":"additional","affiliation":[{"name":"Hotchkiss Brain Institute, Department of Clinical Neurosciences, Cumming School of Medicine University of Calgary  Calgary Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6160-4807","authenticated-orcid":false,"given":"Stephen R.","family":"Duma","sequence":"additional","affiliation":[{"name":"Department of Neurology St George Hospital  Sydney Australia"},{"name":"St George and Sutherland Clinical School, UNSW Medicine  Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Kovacs","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical School University of P\u00e9cs  Baranya Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kigocha Lameck","family":"Okeng'o","sequence":"additional","affiliation":[{"name":"Muhimbili National Hospital  Dar es Salaam Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparna Wagle","family":"Shukla","sequence":"additional","affiliation":[{"name":"Fixel Insititute for Neurological Sciences University of Florida  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6901-2064","authenticated-orcid":false,"given":"Roongroj","family":"Bhidayasiri","sequence":"additional","affiliation":[{"name":"Chulalongkorn Centre of Excellence for Parkinson's Disease &amp; Related Disorders, Department of Medicine, Faculty of Medicine Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society  Bangkok Thailand"},{"name":"The Academy of Science, The Royal Society of Thailand  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago A.","family":"Mestre","sequence":"additional","affiliation":[{"name":"Parkinson's Disease and Movement Disorders Clinic, Division of Neurology, Department of Medicine, The Ottawa Hospital Research Institute University of Ottawa Brain and Mind Institute  Ottawa ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro Sanchez","family":"Ferro","sequence":"additional","affiliation":[{"name":"Movement Disorders Unit, Neurology Department Hospital Universitario 12 de Octubre  Madrid Spain"},{"name":"Centro de Investigacion Biom\u00e9dica en Red sobre Enfermedades Neurodegenerativas (CIBERNED)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto J.","family":"Espay","sequence":"additional","affiliation":[{"name":"James J. and Joan A. 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