{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:39:34Z","timestamp":1790426374923,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Corticobasal syndrome (CBS) is a rare, clinically heterogeneous form of atypical Parkinsonism. Hyperkinetic movements, aside from myoclonus and dystonia, have rarely been reported in CBS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Cases<\/jats:title>\n                    <jats:p>We present two patients with CBS, one with pathologically confirmed corticobasal degeneration (CBD) and generalized chorea, and another with probable CBS and Levodopa\u2010induced dyskinesia (LID). Case 1 exhibited late\u2010onset generalized chorea, which was preceded by several years of dystonia, rigidity and apraxia affecting the right upper limb. Case 2 presented with dystonia, cortical sensory loss, and apraxia in the left upper limb, while LID affected the face and the right side of the body.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Literature Review<\/jats:title>\n                    <jats:p>A systematic review of published cases of chorea or levodopa\u2010induced dyskinesia (LID) in CBS was performed. The literature search was executed in PubMed from its inception for cases of chorea or LID associated with CBS. Twelve patients were identified across eight studies. Only five cases of pathologically confirmed CBD with chorea were found; chorea developed after 4\u2009years of disease progression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Chorea and LID are rare but may represent late manifestations of CBS. The exact mechanisms are unclear; they may relate to variability in anatomical involvement, particularly relative sparing of the GPi. Greater understanding of topographical disease progression may improve diagnostic precision and phenotypic classification in CBS and related tauopathies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70420","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T10:17:57Z","timestamp":1762337877000},"page":"1056-1063","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chorea and Levodopa\u2010Induced Dyskinesia in Corticobasal Syndrome: Two Case Reports with Pathological Insights and Literature Review"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8640-3967","authenticated-orcid":false,"given":"Alex Medina","family":"Escobar","sequence":"first","affiliation":[{"name":"Moncton Interdisciplinary Neurodegenerative Diseases (MIND) Clinic, Horizon Health Network  Moncton New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malco","family":"Rossi","sequence":"additional","affiliation":[{"name":"Servicio de Movimientos Anormales, Departamento de Neurolog\u00eda, FLENI, Ciudad Aut\u00f3noma de Buenos Aires  Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Richer","sequence":"additional","affiliation":[{"name":"Axe neurosciences du Centre de recherche du Centre hospitalier universitaire (CHU) de Qu\u00e9bec\u2010Universit\u00e9 Laval, et D\u00e9partement de biologie mol\u00e9culaire, biochimie et pathologie de l'Universit\u00e9 Laval  Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Gautreau","sequence":"additional","affiliation":[{"name":"Moncton Interdisciplinary Neurodegenerative Diseases (MIND) Clinic, Horizon Health Network  Moncton New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony E.","family":"Lang","sequence":"additional","affiliation":[{"name":"Division of Neurology, Temerty Faculty of Medicine University of Toronto  Toronto Ontario Canada"},{"name":"Edmond J. 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