{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T08:08:51Z","timestamp":1778746131706,"version":"3.51.4"},"reference-count":51,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Bilateral globus pallidus internus deep brain stimulation (GPi\u2010DBS) is a proven safe and effective treatment in certain forms of idiopathic or inherited dystonia (ID\/IN). Its effects in acquired dystonia such as in dyskinetic cerebral palsy (DCP) however vary widely. The impact of GPi\u2010DBS on speech and swallowing, which significantly affect quality of life, remains poorly understood, especially in pediatric patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate GPi\u2010DBS effects on speech and swallowing using the Frenchay Dysarthria Assessment 2 (FDA\u20102), in pediatric patients with dystonia, and assess how the effects differ between DCP and ID\/IN patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This pro\u2010 and retrospective multicenter study analyzes speech and swallowing pre\u2010 and 12\u2009months post\u2010GPi\u2010DBS using FDA\u20102, including prospective data from the STIM\u2010CP trial and retrospective data from the GEPESTIM registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010six patients were included (17 male, 9 female; 14 DCP, 12 ID\/IN) with mean age of 12.2\u2009years at DBS. No significant changes in FDA\u20102 total scores were observed pre\u2010 and post\u2010DBS (pre: 46.3\u2009\u00b1\u200933.6; post: 46.3\u2009\u00b1\u200934.2). ID\/IN patients showed consistently higher scores compared to DCP patients both pre\u2010 and post\u2010DBS (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.005). When adjusted for age, medication, and pre\u2010surgical values, group differences narrowed, with minimal changes from baseline in both groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>GPi\u2010DBS did not significantly change FDA\u20102 scores pre\u2010 and post\u2010DBS. Assessing speech and swallowing in pediatric patients with dystonia, impaired expressive language and\/or intellectual disability is challenging. More comprehensive and patient\u2010centered assessment tools are needed to fully capture DBS effects on these domains in these complex disabled patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70454","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T09:50:16Z","timestamp":1764237016000},"page":"1194-1205","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of Pallidal Deep Brain Stimulation on Speech and Swallowing in Pediatric Patients with Dystonia"],"prefix":"10.1002","volume":"13","author":[{"given":"Katerina","family":"Bernardi","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine and University Hospital Cologne University of Cologne  Cologne Germany"},{"name":"Department Human Neuroscience Sapienza University  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea A.","family":"K\u00fchn","sequence":"additional","affiliation":[{"name":"Department of Neurology and Experimental Neurology, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3291-7222","authenticated-orcid":false,"given":"Ana Lu\u00edsa","family":"de Almeida Marcelino","sequence":"additional","affiliation":[{"name":"Department of Neurology and Experimental Neurology, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Eckenweiler","sequence":"additional","affiliation":[{"name":"Department of Neuropediatrics and Muscle Disorders, University Medical Center, Faculty of Medicine University of Freiburg  Freiburg 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