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Vergence eye movement deficits, characteristics of degenerative cerebellar disease, have not been studied in M\u2010D. Cerebellar transcranial alternating current stimulation (tACS) is considered a potential therapeutic approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess vergence and prosaccade performance as markers of cerebellar dysfunction in M\u2010D and to evaluate the effects of cerebellar 50\u2009Hz tACS on these eye movements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Vergence and prosaccade performance were examined in 14\u2009M\u2010D patients carrying pathogenic\n                      <jats:italic>SGCE<\/jats:italic>\n                      variants and 14 healthy controls. A subgroup (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097) received real and sham 50\u2009Hz cerebellar tACS in a randomized, double\u2010blind design.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>M\u2010D patients showed prolonged latency and reduced gain of convergence compared to controls. Divergence did not differ between groups. Prosaccade peak velocity was reduced in M\u2010D patients. 50\u2009Hz cerebellar tACS showed no effect on eye movements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Impaired convergence supports cerebellar involvement in M\u2010D. Further studies should identify affected pathways.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70521","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T10:32:18Z","timestamp":1768213938000},"page":"1488-1495","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Convergence Deficits in Myoclonus\u2010Dystonia Point to Cerebellar Impairment"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4844-4375","authenticated-orcid":false,"given":"Skadi","family":"Gerkensmeier","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital Schleswig\u2010Holstein  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2229-104X","authenticated-orcid":false,"given":"Christina","family":"Bolte","sequence":"additional","affiliation":[{"name":"Institute of Systems Motor Science, University of L\u00fcbeck  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2115-9603","authenticated-orcid":false,"given":"Jan\u2010Ole","family":"Radecke","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy University of L\u00fcbeck  L\u00fcbeck Germany"},{"name":"Center of Brain, Behavior and Metabolism (CBBM), University of L\u00fcbeck  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1324-2776","authenticated-orcid":false,"given":"Feline","family":"Hamami","sequence":"additional","affiliation":[{"name":"Institute of Systems Motor Science, University of L\u00fcbeck  L\u00fcbeck 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