{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:04:56Z","timestamp":1789704296831,"version":"4.0.1"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Huntington's Disease Behavioral Questionnaire (HD\u2010BQ) captures behavioral symptoms arising from cognitive, psychiatric, and functional domains. Recognizing the high prevalence of anosognosia in HD, the HD\u2010BQ incorporates patient\u2010 and companion\u2010reported versions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Examine the utility of the HD\u2010BQ in capturing behavioral symptoms in HD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The HD\u2010BQ was administered to 71 manifest HD patients and their companions, plus 71 healthy controls (HC). Differences in HD\u2010BQ scores were examined using Mann\u2013Whitney U and Wilcoxon signed\u2010ranks tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      HD patients reported more severe behavioral symptoms than HC (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Companions reported more widespread and severe symptoms than patients (\n                      <jats:italic>Z<\/jats:italic>\n                      \u2009=\u2009\u22123.7,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The largest discrepancies were observed for cognitive items\u2014difficulty shifting thoughts or activities (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), concentrating (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002), keeping track of commitments (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006), judgment (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004), and indecisiveness (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The HD\u2010BQ captures a wide range of behavioral disturbances in HD. Companions consistently reported more frequent and severe symptoms than patients, likely reflecting patients\u2019 anosognosia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70539","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T13:14:59Z","timestamp":1768914899000},"page":"1513-1517","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Capturing Behavioral Symptoms in Huntington's Disease Using the Huntington's Disease\u2010Behavioral Questionnaire"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1557-0516","authenticated-orcid":false,"given":"Siena","family":"Rigatuso","sequence":"first","affiliation":[{"name":"Department of Neurosciences University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6438-1844","authenticated-orcid":false,"given":"Krisha","family":"Bagga","sequence":"additional","affiliation":[{"name":"Department of Neurosciences University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelby","family":"Hughes","sequence":"additional","affiliation":[{"name":"Department of Neurosciences University of California, San Diego  San Diego California USA"},{"name":"Department of Psychology San Diego State University  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6553-0944","authenticated-orcid":false,"given":"Japleen","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Neurosciences University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Gilbert","sequence":"additional","affiliation":[{"name":"Department of Psychology San Diego State University  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jody","family":"Corey\u2010Bloom","sequence":"additional","affiliation":[{"name":"Department of Neurosciences University of California, San Diego  San Diego California 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