{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T09:26:11Z","timestamp":1786785971445,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["2R01NS073717"],"award-info":[{"award-number":["2R01NS073717"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Most fall\u2010prediction models in Parkinson's disease (PD) rely on prior falls, limiting prevention. The\n                      <jats:italic>Waiting Room of the Future<\/jats:italic>\n                      (WROTF) platform collects standardized motor and cognitive measures during routine visits, integrated into electronic health records (EHR).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To develop a first\u2010fall prediction model combining WROTF\u2010EHR data and compare its performance with established cognitive\u2010 and motor\u2010based models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Previously published motor (Paul) and cognitive (CYCLE\u2010II) models were refit using logistic regression. A new regularized (LASSO) model was developed. All models were evaluated using all participants and only those without prior falls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 997 PD patients (mean age 69.6\u2009\u00b1\u20098.8; 62.8% male; disease duration 3.6\u2009\u00b1\u20094.3\u2009years), AUCs were 0.77 (Paul), 0.70 (CYCLE\u2010II), and 0.81 (LASSO). In fall\u2010na\u00efve patients, AUCs were 0.62, 0.68, and 0.70. Key predictors included processing speed, walking speed, disease duration, and age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The model enables early fall\u2010risk detection using routinely collected data, supporting proactive and personalized preventive care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70599","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T04:28:58Z","timestamp":1773635338000},"page":"1940-1946","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Closing the Gate\n                    <i>Before<\/i>\n                    the Horse is out of the Barn: A Model to Effectively Predict the\n                    <i>First Fall<\/i>\n                    in Patients with Parkinson's Disease"],"prefix":"10.1002","volume":"13","author":[{"given":"Saar","family":"Anis","sequence":"first","affiliation":[{"name":"Center for Neurological Restoration Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Munyeshyaka","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Lerner College of Medicine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert H.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anson B.","family":"Rosenfeldt","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay L.","family":"Alberts","sequence":"additional","affiliation":[{"name":"Center for Neurological Restoration Cleveland Clinic  Cleveland Ohio USA"},{"name":"Department of Biomedical Engineering Cleveland Clinic  Cleveland Ohio 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