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There is a lack of evidence to guide the use of enteral nutrition in these situations, including whether it improves survival or reduces aspiration pneumonia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To systematically review the impact of enteral nutrition in Parkinson's disease and atypical parkinsonism on survival and morbidity (including aspiration pneumonia).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We followed PRISMA guidelines and conducted searches using PubMed and Scopus databases. ROBINS\u2010I V2 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20092) and JBI Cohort Study (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200914) checklists were used to assess risk of bias.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 16 eligible studies. Risk of bias was moderate or high in all studies. Reported enteral feeding rates in parkinsonian disorders varied widely. The rate of aspiration pneumonia following enteral feeding was around 40% in those with parkinsonism. The weighted median survival following gastrostomy insertion in Parkinson's disease was 1.35\u2009years (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200983; 3 studies) and in atypical parkinsonism 1.49\u2009years (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200946; 2 studies). One study in atypical parkinsonism found improved survival with enteral feeding compared to at\u2010risk feeding (24 vs. 12\u2009months), whilst another in Parkinson's disease found no difference in mortality rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is a lack of high\u2010quality evidence on the impact of enteral feeding on prognosis and morbidity. It is unclear whether enteral feeding improves survival compared to at\u2010risk feeding. There is a need for more robust evidence such as through enteral feeding registries with standardized data collection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70653","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T07:34:58Z","timestamp":1777620898000},"page":"2104-2115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Enteral Nutrition in Idiopathic Parkinson's Disease and Atypical Parkinsonism: A Systematic Review"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8648-7048","authenticated-orcid":false,"given":"Bradley","family":"Lonergan","sequence":"first","affiliation":[{"name":"Department of Brain Sciences, Charing Cross Hospital, Hammersmith Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2114-4252","authenticated-orcid":false,"given":"Matteo","family":"Ciocca","sequence":"additional","affiliation":[{"name":"Department of Neurology, Charing Cross Hospital, Hammersmith Imperial College Healthcare Trust (ICHT)  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9872-6680","authenticated-orcid":false,"given":"Anette","family":"Schrag","sequence":"additional","affiliation":[{"name":"Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3987-0113","authenticated-orcid":false,"given":"Yen","family":"Tai","sequence":"additional","affiliation":[{"name":"Department of Brain Sciences, Charing Cross Hospital, Hammersmith Imperial College London  London UK"},{"name":"Department of Neurology, Charing Cross Hospital, Hammersmith Imperial College Healthcare Trust (ICHT)  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000112902"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.60.6.615"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.58.2.259"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.2373-18"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.039370"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2016.05.034"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2008.11.005"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10583"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-021-10739-8"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2021.120008"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1044\/2021_AJSLP-21-00145"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.2009.01031.x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/174_2017_101"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-013-7232-4"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0135823"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S97481"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03501.x"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181d38ced"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/2040-7378-5-14"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2015.09.004"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12924"},{"key":"e_1_2_11_23_1","unstructured":"NICE.Dementia: Assessment management and support for people living with dementia and their carers;2018. 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