{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:53:25Z","timestamp":1777949605218,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100017336","name":"Dipartimenti di Eccellenza","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Socio\u2010occupational functioning in patients with Parkinson's disease (PD) treated with subthalamic nucleus deep brain stimulation (STN\u2010DBS) is not fully captured by standard motor and quality\u2010of\u2010life scales.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To characterize patient\u2010reported socio\u2010occupational functioning after STN\u2010DBS and explore associated clinical and demographic factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010four PD patients were assessed 9\u201318\u2009months postoperatively using a semi\u2010structured interview covering socio\u2010occupational domains. A composite mean score (Q_mean) was computed as a descriptive index, with clinical associations explored using univariate screening and multivariate linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The Q_mean score following STN\u2010DBS was 7.66\u2009\u00b1\u20090.86 (range 6.00\u20139.57). In exploratory multivariate analysis, female sex (n\u2009=\u20097) was associated with higher functioning (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.003), whereas GBA variants (n\u2009=\u20095) with lower functioning (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.007).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Perceived socio\u2010occupational functioning was overall satisfactory at postoperative assessment, with limited association with conventional motor\/neuropsychiatric measures, and greater association with individual factors such as sex and genetic background. These exploratory findings support inclusion of socio\u2010occupational perspectives in DBS outcome evaluation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70661","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:56:21Z","timestamp":1777704981000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Socio\u2010Occupational Functioning after Subthalamic Deep Brain Stimulation in Parkinson's Disease"],"prefix":"10.1002","author":[{"given":"Gabriele","family":"Imbalzano","sequence":"first","affiliation":[{"name":"Department of Neuroscience \u201cRita Levi Montalcini\u201d University of Turin  Turin Italy"},{"name":"SC Neurologia 2U, AOU Citt\u00e0 della Salute e della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Montanaro","sequence":"additional","affiliation":[{"name":"Clinical Psychology Unit, AOU Citt\u00e0 Della Salute e Della Scienza di Torino  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Giacchero","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Turin  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Ledda","sequence":"additional","affiliation":[{"name":"Department of Neuroscience \u201cRita Levi Montalcini\u201d University of Turin  Turin Italy"},{"name":"SC Neurologia 2U, AOU Citt\u00e0 della Salute e della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Romagnolo","sequence":"additional","affiliation":[{"name":"Department of Neuroscience \u201cRita Levi Montalcini\u201d University of Turin  Turin Italy"},{"name":"SC Neurologia 2U, AOU Citt\u00e0 della Salute e della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario Giorgio","family":"Rizzone","sequence":"additional","affiliation":[{"name":"Department of Neuroscience \u201cRita Levi Montalcini\u201d University of Turin  Turin Italy"},{"name":"SC Neurologia 2U, AOU Citt\u00e0 della Salute e della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Lopiano","sequence":"additional","affiliation":[{"name":"Department of Neuroscience \u201cRita Levi Montalcini\u201d University of Turin  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2939-343X","authenticated-orcid":false,"given":"Maurizio","family":"Zibetti","sequence":"additional","affiliation":[{"name":"Department of Neuroscience \u201cRita Levi Montalcini\u201d University of Turin  Turin Italy"},{"name":"SC Neurologia 2U, AOU Citt\u00e0 della Salute e della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29052"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-211-45295-0_61"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2016.01.019"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26468"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.13015"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.72.1.53"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29410"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.15558"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28390"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3171\/2025.1.JNS241670"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ane.12127"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2023-332387"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000214036"}],"container-title":["Movement 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