{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T07:40:15Z","timestamp":1792482015291,"version":"4.5.0"},"reference-count":41,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100004312","name":"Eli Lilly and Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Penn Parkinson's Daily Activities Questionnaire\u201027 (PDAQ\u201027) is a 27\u2010item measure of cognitive instrumental activities of daily living (IADLs) for Parkinson's disease (PD) patients developed by integrating 12 additional items with the original 15\u2010item PDAQ\u201015 via mixed\u2010methods research with the goal of creating a more balanced and sensitive instrument.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the psychometric properties of the PDAQ\u201027 in a PD cohort using both patient and knowledgeable informant (KI) responses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study of 114 PD participants was conducted. Participants and, when available, KIs completed the PDAQ\u201027. Psychometric properties were evaluated using Rasch Measurement Theory (RMT) and Classical Test Theory (CTT). Consistency between patient\u2010 and KI\u2010reported versions was assessed using RMT framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The PDAQ\u201027 demonstrated strong reliability (Cronbach's alpha\u2009=\u20090.95; Person Separation Index\u2009=\u20090.93) and good Rasch model fit, with no significant local dependency or differential item functioning. The PDAQ\u201027 total score correlated moderately with cognitive tests (eg, DRS\u20102 total:\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.37; MoCA:\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.30), and health\u2010related quality of life (HRQoL) measures (eg, PDQ\u201039 cognition domain:\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.65), supporting construct validity. Compared with the PDAQ\u201015, the PDAQ\u201027 marginally improved coverage of mild cognitive IADL impairments, though low\u2010end discrimination remained limited. Patient and KI scores were highly correlated and largely equivalent, despite differing response patterns reflecting the different perspectives of patients and KIs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The PDAQ\u201027 is a promising measure of cognition\u2010related IADLs in patients with PD, with solid cross\u2010sectional psychometric performance. Further research on its longitudinal properties will be needed to recommend its future use in PD studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70677","type":"journal-article","created":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T11:33:47Z","timestamp":1780313627000},"page":"2526-2538","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychometric Evidence for an Augmented\n                    <scp>PDAQ<\/scp>\n                    for Improved Measurement of Cognition\u2010Related\n                    <scp>IADLs<\/scp>\n                    in Parkinson's Disease"],"prefix":"10.1002","volume":"13","author":[{"given":"Antoine","family":"Regnault","sequence":"first","affiliation":[{"name":"Modus Outcomes  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Delbecque","sequence":"additional","affiliation":[{"name":"Eli Lilly and Company  Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manal","family":"M'Hari","sequence":"additional","affiliation":[{"name":"Modus Outcomes  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3854-632X","authenticated-orcid":false,"given":"Flora","family":"Mazerolle","sequence":"additional","affiliation":[{"name":"Modus Outcomes  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5114-3755","authenticated-orcid":false,"given":"Kevin","family":"Biglan","sequence":"additional","affiliation":[{"name":"Eli Lilly and Company  Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Chandler","sequence":"additional","affiliation":[{"name":"Eli Lilly and Company  Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0854-5611","authenticated-orcid":false,"given":"Izabelle","family":"Schoen","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenia","family":"Mamikonyan","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Siderowf","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0633-7168","authenticated-orcid":false,"given":"Daniel","family":"Weintraub","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26373"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/114.5.2095"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20527"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181f39d0e"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21956"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.3.387"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0891988712464823"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1166(199910)14:10<866::AID-GPS38>3.0.CO;2-Z"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000306632.43729.24"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/neu0000045"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000201201"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2016.02.020"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26339"},{"key":"e_1_2_10_15_1","doi-asserted-by":"crossref","unstructured":"WeintraubD SiderowfA MamikonyanE et al.Improving the conceptual coverage of the 15\u2010item Penn Parkinson's Daily Activity Questionnaire (PDAQ\u201015) for use in the mild\u2010to\u2010moderate Lewy body dementia population. presented at: ISPOR 2025: Europe; 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