{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T03:03:29Z","timestamp":1784257409020,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dystonia after focal thalamic lesions including from high\u2010intensity focused ultrasound (HiFU) ablation have been reported. The risk remains uncertain and is increasingly relevant given the exponential rise in thalamic interventions for tremor over the last decade.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the frequency and magnitude of dystonia before and after thalamic HiFU ablation in individuals with essential and dystonic tremor.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A blinded video\u2010based analysis was performed using standardized dystonia and tremor rating scales at baseline and two follow\u2010up intervals. Generalized linear mixed models assessed longitudinal change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty individuals met the inclusion\/exclusion criteria. Whole body and treated limb dystonia severity did not significantly change over time. One individual developed clinically significant dystonia after treatment yielding an estimated risk of approximately 1\u20132%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Dystonic features were identified in all individuals at baseline, including those diagnosed with essential tremor. Thalamic HiFU ablation was not associated with progression of dystonia severity during follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70743","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T02:06:58Z","timestamp":1784254018000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dystonia before and after Unilateral High Intensity Focused Ultrasound Thalamotomy in Essential and Dystonic Tremor"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7533-4388","authenticated-orcid":false,"given":"James","family":"Peters","sequence":"first","affiliation":[{"name":"Department of Neurology St Vincent's Health Network  Sydney New South Wales Australia"},{"name":"School of Medical Sciences The University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Maamary","sequence":"additional","affiliation":[{"name":"Department of Neurology St Vincent's Health Network  Sydney New South Wales Australia"},{"name":"School of Medical Sciences The University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyndsey","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Neurology St Vincent's Health Network  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Barnett","sequence":"additional","affiliation":[{"name":"School of Medical Sciences The University of New South Wales  Sydney New South Wales Australia"},{"name":"Department of Radiology St Vincent's Health Network  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Jonker","sequence":"additional","affiliation":[{"name":"School of Medical Sciences The University of New South Wales  Sydney New South Wales Australia"},{"name":"Department of Neurosurgery St Vincent's Health Network  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2483-1816","authenticated-orcid":false,"given":"Stephen","family":"Tisch","sequence":"additional","affiliation":[{"name":"Department of Neurology St Vincent's Health Network  Sydney New South Wales Australia"},{"name":"School of Medical Sciences The University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1056\/NEJMoa1600159","article-title":"A randomized trial of focused ultrasound Thalamotomy for essential tremor","volume":"375","author":"Elias WJ","year":"2016","journal-title":"N Engl J Med"},{"key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/mds.29658","article-title":"Outcomes of focused ultrasound Thalamotomy in tremor syndromes","volume":"39","author":"Peters J","year":"2024","journal-title":"Mov Disord"},{"key":"e_1_2_10_4_1","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/mds.30188","article-title":"Efficacy and safety of magnetic resonance\u2010guided focused ultrasound Thalamotomy in essential tremor: a systematic review and Metanalysis","volume":"40","author":"Shiramba A","year":"2025","journal-title":"Mov Disord"},{"key":"e_1_2_10_5_1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1136\/jnnp-2020-324061","article-title":"Adoption of focused ultrasound thalamotomy for essential tremor: why so much fuss about FUS?","volume":"92","author":"Iorio\u2010Morin C","year":"2021","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"e_1_2_10_6_1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/mds.870090502","article-title":"Movement disorders following lesions of the thalamus or subthalamic region","volume":"9","author":"Lee MS","year":"1994","journal-title":"Mov Disord"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.parkreldis.2019.11.019","article-title":"Dystonia following thalamic neurosurgery: a single centre experience with MR\u2010guided focused ultrasound thalamotomy","volume":"71","author":"Martino D","year":"2020","journal-title":"Parkinsonism Relat Disord"},{"key":"e_1_2_10_8_1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.parkreldis.2019.08.008","article-title":"Dystonia as complication of thalamic neurosurgery","volume":"66","author":"Picillo M","year":"2019","journal-title":"Parkinsonism Relat Disord"},{"key":"e_1_2_10_9_1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/mds.27121","article-title":"Consensus statement on the classification of tremors. From the task force on tremor of the International Parkinson and Movement Disorder Society: IPMDS task force on tremor consensus statement","volume":"33","author":"Bhatia KP","year":"2018","journal-title":"Mov Disord"},{"key":"e_1_2_10_10_1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1212\/WNL.35.1.73","article-title":"Validity and reliability of a rating scale for the primary torsion dystonias","volume":"35","author":"Burke RE","year":"1985","journal-title":"Neurology"},{"key":"e_1_2_10_11_1","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.parkreldis.2005.05.009","article-title":"Quality of life in essential tremor questionnaire (QUEST): development and initial validation","volume":"11","author":"Tr\u00f6ster AI","year":"2005","journal-title":"Parkinsonism Relat Disord"},{"key":"e_1_2_10_12_1","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000210209","article-title":"Challenges in describing tremor and dystonia","volume":"104","author":"Shaikh 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and drawing by essential tremor phenotype","volume":"3","author":"Peters J","year":"2021","journal-title":"BMJ Neurol Open"},{"key":"e_1_2_10_20_1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/mdc3.13941","article-title":"Essential tremor and essential tremor plus are essentially similar Electrophysiologically","volume":"11","author":"Rajan R","year":"2024","journal-title":"Mov Disord Clin Pract"},{"key":"e_1_2_10_21_1","doi-asserted-by":"crossref","first-page":"9317","DOI":"10.1523\/JNEUROSCI.1181-20.2020","article-title":"The pathophysiology of dystonic tremors and comparison with essential tremor","volume":"40","author":"Panyakaew P","year":"2020","journal-title":"J Neurosci"},{"key":"e_1_2_10_22_1","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1002\/mds.23481","article-title":"Pre\u2010operative evaluations for DBS in dystonia","volume":"26","author":"Thobois S","year":"2011","journal-title":"Mov Disord"}],"container-title":["Movement Disorders 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