{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T06:02:29Z","timestamp":1790056949515,"version":"4.0.1"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008539","name":"CurePSP","doi-asserted-by":"publisher","award":["684\u20102023\u201006\u2010Pathway"],"award-info":[{"award-number":["684\u20102023\u201006\u2010Pathway"]}],"id":[{"id":"10.13039\/100008539","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000957","name":"Alzheimer's Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000957","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Fluid intelligence (\n g<\/jats:italic>\n ) contributes to executive\u2010task performance, but its role in progressive supranuclear palsy (PSP) remains unclear.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n To examine whether executive deficits in PSP are explained by reductions in\n g<\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Thirty\u2010five PSP patients, 39 Parkinson's disease (PD) patients and 18 healthy controls underwent neuropsychological assessment.\n G<\/jats:italic>\n was derived using principal component analysis from non\u2010executive cognitive measures. Group differences in executive performance were examined before and after controlling for\n g<\/jats:italic>\n . Healthy controls provided contextual comparison.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n In PSP versus PD, differences in phonemic fluency and TMT\u2010B were no longer significant after controlling for\n g<\/jats:italic>\n , whereas WCST categories remained significant. In PSP versus healthy controls, WCST and phonemic fluency remained significant after controlling for\n g<\/jats:italic>\n . Sensitivity analyses in cognitively preserved participants showed similar results.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Executive deficits in PSP are partly associated with reduced\n g<\/jats:italic>\n , but cognitive flexibility appears to reflect an additional disease\u2010related impairment.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/mdc3.70821","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T05:18:43Z","timestamp":1790054323000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fluid Intelligence and Executive Dysfunction in Progressive Supranuclear Palsy"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9820-2599","authenticated-orcid":false,"given":"Federico","family":"Castano","sequence":"first","affiliation":[{"name":"Institute of Cognitive Neurology (INECO) Buenos Aires Argentina"},{"name":"Laboratory of Progressive Neuromotor and Neurobehavioral Disorders at Instituto de Neurociencia Cognitiva y Traslacional (INCYT) Buenos Aires Argentina"},{"name":"Pontificia Universidad Cat\u00f3lica Argentina Santa Mar\u00eda de los Buenos Aires Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Roca","sequence":"additional","affiliation":[{"name":"Institute of Cognitive Neurology (INECO) Buenos Aires Argentina"},{"name":"Laboratory of Language and Neuropsychology at Instituto de Neurociencia Cognitiva y Traslacional (INCYT) Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9695-2764","authenticated-orcid":false,"given":"John","family":"Duncan","sequence":"additional","affiliation":[{"name":"Cognition and Brain Science Unit MRC Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3512-7488","authenticated-orcid":false,"given":"Blas","family":"Couto","sequence":"additional","affiliation":[{"name":"Institute of Cognitive Neurology (INECO) Buenos Aires Argentina"},{"name":"Laboratory of Progressive Neuromotor and Neurobehavioral Disorders at Instituto de Neurociencia Cognitiva y Traslacional (INCYT) Buenos Aires Argentina"},{"name":"Laboratory of Language and Neuropsychology at Instituto de Neurociencia Cognitiva y Traslacional (INCYT) Buenos Aires Argentina"},{"name":"Neurology Favaloro University Buenos Aires Argentina"},{"name":"Movement Disorders Unit Institute of Neuroscience of the Fundacion Favaloro Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2307\/1412107"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2013.01.008"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp269"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0231868"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291712000451"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458507084270"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2014.00046"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26987"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26424"},{"key":"e_1_2_9_11_1","volume-title":"RStudio: Integrated Development Environment for R. Version 2026.4.0.526","author":"team P","year":"2026"}],"container-title":["Movement Disorders Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.70821","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mdc3.70821","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mdc3.70821","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T05:18:44Z","timestamp":1790054324000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mdc3.70821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,21]]},"references-count":10,"alternative-id":["10.1002\/mdc3.70821"],"URL":"https:\/\/doi.org\/10.1002\/mdc3.70821","archive":["Portico"],"relation":{},"ISSN":["2330-1619","2330-1619"],"issn-type":[{"value":"2330-1619","type":"print"},{"value":"2330-1619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,21]]},"assertion":[{"value":"2026-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"mdc3.70821"}}