{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:51:21Z","timestamp":1791352281409,"version":"4.3.1"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["movementdisorders.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Movement Disord Clin Pract"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Parkinson's disease (PD) symptoms affects quality of life (QoL), but effects on life satisfaction (LS) are less studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study explored influences of motor and non\u2010motor symptoms on QoL and LS in people with PD in Ireland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eight hundred twenty nine people with PD completed a survey of validated tools, exploring motor and non\u2010motor symptoms, social connectedness, self\u2010efficacy, and stigma, and QoL and LS. Linear and multiple regression analyses assessed influences on QoL and LS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Stigma and low self\u2010efficacy were associated with poor QoL and LS; low social connectedness, dexterity issues, anxiety and apathy were associated with poor LS. Higher symptom burden, particularly dexterity, tremor, bradykinesia, freezing, cognition, psychosis, apathy, daytime sleepiness and urinary problems were associated with low QoL, but less than stigma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Policies to improve QoL and LS should target stigma and low self\u2010efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mdc3.70834","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:38:17Z","timestamp":1791351497000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Influence of Symptoms and Psychosocial Factors on Quality of Life and Life Satisfaction in Parkinson's Disease"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6898-2520","authenticated-orcid":false,"given":"Francesca","family":"Gaiera","sequence":"first","affiliation":[{"name":"Centre for Gerontology and Rehabilitation, School of Medicine University College Cork  Cork Ireland"},{"name":"Parkinson's Disease Research Cluster, College of Medicine &amp; Health University College Cork  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1148-0471","authenticated-orcid":false,"given":"Emma","family":"O'Shea","sequence":"additional","affiliation":[{"name":"Centre for Gerontology and Rehabilitation, School of Medicine University College Cork  Cork Ireland"},{"name":"Parkinson's Disease Research Cluster, College of Medicine &amp; Health University College Cork  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5149-0933","authenticated-orcid":false,"given":"Gerard W.","family":"O'Keeffe","sequence":"additional","affiliation":[{"name":"Parkinson's Disease Research Cluster, College of Medicine &amp; Health University College Cork  Cork Ireland"},{"name":"Department of Anatomy and Neuroscience, School of Medicine University College Cork  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5181-4958","authenticated-orcid":false,"given":"Zahra","family":"Azizi","sequence":"additional","affiliation":[{"name":"Dublin City University Insight Centre for Data Analytics  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7790-9552","authenticated-orcid":false,"given":"Suzanne","family":"Timmons","sequence":"additional","affiliation":[{"name":"Centre for Gerontology and Rehabilitation, 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