{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:08:08Z","timestamp":1763035688455,"version":"build-2065373602"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,4,2]],"date-time":"2002-04-02T00:00:00Z","timestamp":1017705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Paroxysmal dystonic choreoathetosis (PDC) is an episodic, non\u2010kinesogenic, extrapyramidal movement disorder. It is postulated that PDC is an ion channel disorder. We describe a sporadic case of paroxysmal dystonic choreoathetosis occurring after streptococcal pharyngitis. The episodes were characterized by abrupt\u2010onset dystonic posturing, choreoathetosis, visual hallucinations and behavioral disturbance. Each episode lasted between 10 minutes and 4 hours, and occurred up to 4 times per day. In between attacks, examination was normal. The episodes waxed and waned in frequency during a 6\u2010month illness. Magnetic resonance imaging of the brain was normal. Post\u2010streptococcal neuropsychiatric disease has a proposed autoimmune etiology, which is supported by the presence of serum antibasal ganglia antibodies. Western immunoblotting of this case's serum demonstrated antibody binding to a basal ganglia antigens of molecular weight 80 kDa and 95 kDa. Immunohistochemistry examination demonstrated specific antibody binding to large striatal neurones. We propose that autoantibodies produced in post\u2010streptococcal neuropsychiatric disease cause alteration in neurotransmission, possibly secondary to ion channel binding. \u00a9 2002 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.10169","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T07:44:15Z","timestamp":1033890255000},"page":"817-820","source":"Crossref","is-referenced-by-count":45,"title":["Post\u2010Streptococcal autoimmune neuropsychiatric disease presenting as paroxysmal dystonic choreoathetosis"],"prefix":"10.1002","volume":"17","author":[{"given":"Russell C.","family":"Dale","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Church","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.H.","family":"Surtees","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward J.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin","family":"Giovannoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian G.R.","family":"Neville","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,7,22]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050325"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.12.2125"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200008000-00015"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.155.2.264"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.6.1618"},{"key":"e_1_2_7_7_2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1542\/peds.92.1.39","article-title":"Antineuronal antibodies in movement disorders","volume":"92","author":"Kiessling LS","year":"1993","journal-title":"Pediatrics"},{"key":"e_1_2_7_8_2","first-page":"310","volume-title":"Movement disorders 3","author":"Fahn S","year":"1994"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870100403"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8257(199901)14:1<177::AID-MDS1037>3.0.CO;2-N"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19991215)88:6<733::AID-AJMG27>3.0.CO;2-3"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.10169","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.10169","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:26:37Z","timestamp":1760955997000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.10169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,7]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,7]]}},"alternative-id":["10.1002\/mds.10169"],"URL":"https:\/\/doi.org\/10.1002\/mds.10169","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"type":"print","value":"0885-3185"},{"type":"electronic","value":"1531-8257"}],"subject":[],"published":{"date-parts":[[2002,7]]}}}