{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:31:43Z","timestamp":1761006703505,"version":"build-2065373602"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,10,29]],"date-time":"2002-10-29T00:00:00Z","timestamp":1035849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2003,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We studied 12 non\u2010demented PD patients in <jats:italic>on<\/jats:italic> state before and 3 months after posteroventral pallidotomy (PVP), in order to evaluate the effects of surgery upon an unconstrained, multijoint skilled movement as well as a single joint, repetitive, ballistic movement. A Selspot II System was used for three\u2010dimensional data acquisition, processing and reconstruction of limb trajectories. Specific wrist kinematic features of spatial accuracy (linearity and planarity), temporal attributes (acceleration and velocity), spatiotemporal relationships (velocity\u2010curvature coupling), and joint kinematic variables (relationships between wrist and elbow velocities and relative arm angle amplitudes) for each cycle of movement were graphically and numerically analysed. QMC was applied to single joint, repetitive, ballistic movements. QMC significantly improved after PVP (<jats:italic>P<\/jats:italic> &lt; 0.0006). However, wrist as well as joint kinematic variables of the gestural movements failed to change significantly after PVP. The lack of improvement of the kinematic abnormalities of the gestural movement in PD patients would indicate that they are unrelated to the basic motor deficit; most likely they are the result of a disruption of a complex of sensorimotor integration processes due to abnormal parieto\u2010frontal basal ganglia interaction. \u00a9 2002 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.10336","type":"journal-article","created":{"date-parts":[[2003,3,18]],"date-time":"2003-03-18T17:59:21Z","timestamp":1048010361000},"page":"280-286","source":"Crossref","is-referenced-by-count":1,"title":["Pallidotomy in Parkinson's disease improves single\u2010joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements"],"prefix":"10.1002","volume":"18","author":[{"given":"Marcelo","family":"Merello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Balej","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramon","family":"Leiguarda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,10,29]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.4.753"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)92404-3"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199903000-00011"},{"key":"e_1_2_5_5_2","first-page":"158","article-title":"Effects of pallidotomy on Parkinson's patients; comparisons on a computer trajectory paradigm","volume":"11","author":"Simuni T","year":"1996","journal-title":"Mov Disord"},{"key":"e_1_2_5_6_2","first-page":"186","article-title":"Pallidotomy improves the accuracy and trajectory of 3\u2010dimensional pointing movements in Parkinson's disease: a case study","volume":"11","author":"Fookson O","year":"1996","journal-title":"Mov Disord"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.62.2.125"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.65.4.479"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1353-8020(97)00033-3"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8257(200007)15:4<627::AID-MDS1006>3.0.CO;2-5"},{"key":"e_1_2_5_11_2","first-page":"55","article-title":"Three\u2010dimensional movement analysis of gestural and repetitive self\u2010paced single joint rapid arm movements in Parkinson's disease","volume":"15","author":"Merello M","year":"2000","journal-title":"Mov Disord"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.2.315"},{"key":"e_1_2_5_13_2","series-title":"Control of arm movements in space. 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