{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:18:51Z","timestamp":1780460331710,"version":"3.54.1"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2003,6,6]],"date-time":"2003-06-06T00:00:00Z","timestamp":1054857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report on a family with ataxia type 6 (SCA6) showing peculiar oculomotor symptoms. The proband presented with periodic alternating nystagmus (PAN), and her 2 brothers had rebound nystagmus and gaze\u2010evoked nystagmus. They carried the identical mutation (the number of expanded CAG repeat, 24) in the <jats:italic>CACNA1A<\/jats:italic> gene. The intrafamilial variability of oculomotor symptoms may be ascribed to factors other than CAG repeat expansion size in SCA6. \u00a9 2003 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.10511","type":"journal-article","created":{"date-parts":[[2003,10,6]],"date-time":"2003-10-06T03:04:21Z","timestamp":1065409461000},"page":"1201-1204","source":"Crossref","is-referenced-by-count":28,"title":["Periodic alternating nystagmus and rebound nystagmus in spinocerebellar ataxia type 6"],"prefix":"10.1002","volume":"18","author":[{"given":"Takao","family":"Hashimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunihiro","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yo\u2010ichi","family":"Takei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu\u2010ichi","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,10]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0197-62"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.49.5.1238"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.49.5.1243"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.49.5.1247"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410420616"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-198708000-00006"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(71)90014-6"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/99.1.11"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490350057009"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1981.tb30906.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.45.12.1170"},{"key":"e_1_2_5_13_2","first-page":"512","article-title":"Periodic alternating nystagmus in spinocerebellar ataxia type6 (SCA 6)","volume":"38","author":"Yabe I","year":"1998","journal-title":"Clin Neurol (Tokyo)"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1980.00500520076016"},{"key":"e_1_2_5_15_2","first-page":"230","article-title":"Primidone\/phenobarbital\u2010induced periodic alternating nystagmus","volume":"21","author":"Schwankhaus JD","year":"1989","journal-title":"Ann Ophthalmol"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.3871968"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/96.3.507"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410150512"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1981.46.4.878"},{"key":"e_1_2_5_20_2","first-page":"119","article-title":"A familial factor independent of CAG repeat length influences age at onset of Machado\u2010Joseph disease","volume":"59","author":"DeStefano AL","year":"1996","journal-title":"Am J Hum Genet"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.10511","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.10511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:27:10Z","timestamp":1760970430000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.10511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,10]]},"references-count":19,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2003,10]]}},"alternative-id":["10.1002\/mds.10511"],"URL":"https:\/\/doi.org\/10.1002\/mds.10511","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,10]]}}}