{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:28:38Z","timestamp":1791350918957,"version":"4.3.1"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2003,9,26]],"date-time":"2003-09-26T00:00:00Z","timestamp":1064534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2003,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We sought to determine the prevalence and nature of sweating disturbances in patients with Parkinson's disease (PD), and investigated their correlation with other clinical features and with Quality of Life (QoL) measures. A questionnaire on symptoms and consequences of sweating dysfunction was completed by 77 consecutive outpatients, from three movement disorder clinics, and 40 controls. QoL was assessed using the disease\u2010specific Parkinson's Disease Questionnaire (PDQ)\u201039 and generic EuroQoL (EQ)\u20105D rating scales. Patients also underwent a clinical examination, including assessment with the Unified Parkinson's Disease Rating Scale and the Hoehn and Yahr staging system. Sweating disturbances, either hypohidrosis or in particular, hyperhidrosis, were reported by 64% of patients and by 12.5% of controls (<jats:italic>P<\/jats:italic> &lt; 0.005) and were often localised or asymmetric. Complaints of sweating disturbances were not correlated with disease severity, but did correlate with other symptoms of autonomic dysfunction. Sweating problems occurred predominantly in <jats:italic>off<\/jats:italic> periods and in <jats:italic>on<\/jats:italic> periods with dyskinesias. Sweating disturbances were not correlated with overall QoL scores, but we did observe a significant correlation with the pain dimension of the PDQ\u201039 and the visual analogue scale of the EQ\u20105D. Furthermore, many patients reported physical, social, and emotional impairment due to sweating. Sweating disturbances are common and distressing symptoms of PD that are related mainly to autonomic dysfunction, off periods, and dyskinesias. \u00a9 2003 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.10586","type":"journal-article","created":{"date-parts":[[2003,12,10]],"date-time":"2003-12-10T05:00:27Z","timestamp":1071032427000},"page":"1459-1463","source":"Crossref","is-referenced-by-count":147,"title":["Sweating dysfunction in Parkinson's disease"],"prefix":"10.1002","volume":"18","author":[{"given":"Lesley","family":"Swinn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette","family":"Schrag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramchandran","family":"Viswanathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastiaan 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