{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T10:55:45Z","timestamp":1776164145333,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,9,29]],"date-time":"2003-09-29T00:00:00Z","timestamp":1064793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2004,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Akinesia is associated with supplementary motor area (SMA) dysfunction in Parkinson's disease. We looked for a similar association in patients with schizophrenia. Using functional magnetic resonance imaging (fMRI), we compared motor activation in 6 akinetic neuroleptic\u2010treated schizophrenic patients and 6 normal subjects. Schizophrenic patients had a defective activation in the SMA, left primary sensorimotor cortex, bilateral lateral premotor and inferior parietal cortices, whereas the right primary sensorimotor cortex and a mesial frontal area were hyperactive. SMA was hypoactive in akinetic schizophrenic patients, emphasizing the role of this area in motor slowness. Other abnormal signals likely reflect schizophrenia\u2010related abnormal intracortical connections. \u00a9 2003 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.10598","type":"journal-article","created":{"date-parts":[[2004,1,21]],"date-time":"2004-01-21T05:01:49Z","timestamp":1074661309000},"page":"83-90","source":"Crossref","is-referenced-by-count":30,"title":["Cortical motor activation in akinetic schizophrenic patients: A pilot functional MRI study"],"prefix":"10.1002","volume":"19","author":[{"given":"Pierre","family":"Payoux","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kader","family":"Boulanouar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Sarramon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelly","family":"Fabre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Descombes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique","family":"Galitsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Thalamas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Brefel\u2010Courbon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto","family":"Sabatini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claude","family":"Manelfe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Chollet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Schmitt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Rascol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,1,6]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410320206"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1992.00530260044017"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.57.5.567"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0920-9964(91)90017-L"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.167.2.197"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199709080-00034"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.1998.0387"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2007.00818.x"},{"key":"e_1_2_6_10_2","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_6_11_2","first-page":"261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"12","author":"Kay SR","year":"1987","journal-title":"Schizophr Bull"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.2.394"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.460020402"},{"key":"e_1_2_6_14_2","volume-title":"Co\u2010planar stereotaxic atlas of the human brain","author":"Talairach J","year":"1988"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.6.963"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(84)91341-6"},{"key":"e_1_2_6_17_2","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1523\/JNEUROSCI.04-02-00539.1984","article-title":"The origin of thalamic inputs to the accurate premotor and supplementary motor areas","volume":"4","author":"Schell GR","year":"1984","journal-title":"J Neurosci"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870010405"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/112.1.233"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(94)00206-4"},{"key":"e_1_2_6_21_2","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0166-2236(90)90110-V","article-title":"Primate models of movement disorder of basal ganglia origin","volume":"13","author":"DeLong M","year":"1990","journal-title":"Trends Neurosci"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-9964(99)00032-8"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5846(01)00271-8"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-199405020-00006"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-8206.1994.tb00808.x"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a033361"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.4.347"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.10.1985"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/121.3.527"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.130177397"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/378176a0"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.3.604"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/0920-9964(95)00000-3"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.10598","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.10598","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:49:19Z","timestamp":1760953759000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.10598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,1]]}},"alternative-id":["10.1002\/mds.10598"],"URL":"https:\/\/doi.org\/10.1002\/mds.10598","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,1]]}}}