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A structured interview of 50 patients with higher dopamine replacement therapy requirements (&gt;800 levodopa equivalent units\/day) from 123 unselected patients with Parkinson's disease (PD) from a PD clinic identified 17 (14%) patients with punding. Punding was acknowledged as disruptive and unproductive by the patients themselves, but forcible attempts by family to interrupt the behaviour led to irritability and dysphoria. Punding was associated with very high doses of dopamine replacement therapy often related to a pattern of chronic inappropriate overuse of dopaminergic medication. We believe that this is an underreported, socially disabling phenomenon that is commonly associated with the syndrome of dopamine dysregulation and is phenomenologically distinct from both obsessive\u2010compulsive disorder and mania. \u00a9 2004 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.20045","type":"journal-article","created":{"date-parts":[[2004,3,25]],"date-time":"2004-03-25T12:32:10Z","timestamp":1080217930000},"page":"397-405","source":"Crossref","is-referenced-by-count":445,"title":["Punding in Parkinson's disease: Its relation to the dopamine dysregulation syndrome"],"prefix":"10.1002","volume":"19","author":[{"given":"Andrew 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