{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T19:21:10Z","timestamp":1762111270242,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T00:00:00Z","timestamp":1113523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe the case of an adult female with Hallervorden\u2013Spatz disease (HSD), \u201ceye\u2010of\u2010the\u2010tiger\u201d sign on cranial magnetic resonance imaging scan, and two mutations in the pantothenate kinase 2 (PANK2) gene. Symptomatic presentation included stuttering dysarthria, dystonic posturing, increased limb and axial muscle tone, choreoathetosis, stereotyped motor behaviors, and obsessive\u2013compulsive symptomatology since adolescence. Extensive neuropsychological testing at 40 and 44 years of age revealed a relatively normal IQ and stable cognitive pattern overall. This case demonstrates that HSD patients who survive into middle age should not be assumed to have a progressive dementia. In such cases, atypical behavioral problems such as persistent obsessions and compulsions may be present instead. \u00a9 2005 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.20476","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T19:16:43Z","timestamp":1113592603000},"page":"880-886","source":"Crossref","is-referenced-by-count":15,"title":["Atypical Hallervorden\u2013Spatz disease with preserved cognition and obtrusive obsessions and compulsions"],"prefix":"10.1002","volume":"20","author":[{"given":"Anthony P.","family":"Nicholas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly S.","family":"Earnst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel C.","family":"Marson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,4,15]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02878455"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490310072012"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(95)00212-K"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(01)00253-3"},{"key":"e_1_2_6_6_2","series-title":"Handbook of clinical neurology: diseases of the basal ganglia","first-page":"604","author":"Wigboldus JM","year":"1968"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(01)00269-7"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.39.3.440"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1991.00530240091029"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.217.3.r00dc31895"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(01)00296-X"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00856805"},{"key":"e_1_2_6_13_2","first-page":"155","article-title":"Hallervorden\u2010Spatz disease: MR and pathologic findings","volume":"14","author":"Savoiardo M","year":"1993","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng572"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020817"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410240519"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010000224"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10105"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870090322"},{"key":"e_1_2_6_20_2","first-page":"66","article-title":"Hallervorden\u2010Spatz disease in a psychiatric setting","volume":"50","author":"Morphy MA","year":"1989","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1979.tb00842.x"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(97)00262-X"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1999.91.2.0313"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.20476","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.20476","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:35:53Z","timestamp":1760952953000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.20476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4,15]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["10.1002\/mds.20476"],"URL":"https:\/\/doi.org\/10.1002\/mds.20476","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"type":"print","value":"0885-3185"},{"type":"electronic","value":"1531-8257"}],"subject":[],"published":{"date-parts":[[2005,4,15]]}}}