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Pathological analysis revealed the presence of Lewy bodies in brainstem nuclei and basal forebrain consistent with Lewy body disease (LBD), as well as motor neuron degeneration and argyrophilic grain disease. We compared our two cases to all previously published pathological cases of combined LBD and motor neuron degeneration. \u00a9 2005 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.20604","type":"journal-article","created":{"date-parts":[[2005,7,20]],"date-time":"2005-07-20T18:33:33Z","timestamp":1121884413000},"page":"1515-1520","source":"Crossref","is-referenced-by-count":16,"title":["Alpha\u2010synuclein immunohistochemistry in two cases of co\u2010occurring idiopathic Parkinson's disease and motor neuron disease"],"prefix":"10.1002","volume":"20","author":[{"given":"Kevin J.","family":"Klos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.","family":"Josephs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.","family":"Parisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis W.","family":"Dickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,7,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.6.1546"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/146608200300079536"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.8.1497"},{"key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1007\/BF03161077","article-title":"Parkinsonism\u2010dementia complex on Guam: overview of clinical aspects","volume":"246","author":"Murakami N","year":"1999","journal-title":"J Neurol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(00)00425-1"},{"key":"e_1_2_6_7_2","first-page":"86","volume-title":"Neurodegeneration: the molecular pathology of dementia and movement disorders","author":"Ghetti B","year":"2003"},{"key":"e_1_2_6_8_2","first-page":"137","volume-title":"Neurodegeneration: the molecular pathology of dementia and movement disorders","author":"Oyanagi K","year":"2003"},{"key":"e_1_2_6_9_2","first-page":"342","volume-title":"Neurodegeneration: the molecular pathology of dementia and movement disorders","author":"Lowe J","year":"2003"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/00004691-199301000-00003","article-title":"Autonomic nervous system function","volume":"10","author":"Low PA","year":"1993","journal-title":"J Clin Neurophysiol"},{"key":"e_1_2_6_11_2","first-page":"217","volume-title":"Clinical autonomic disorders: evaluation and management","author":"Fealey RD","year":"1993"},{"key":"e_1_2_6_12_2","first-page":"S58","article-title":"Idiopathic Parkinson's disease with motor neuron disease","volume":"13","author":"Josephs KA","year":"2003","journal-title":"Brain Pathol"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00309344"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1996.00550100061015"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.039479"},{"key":"e_1_2_6_16_2","first-page":"163","article-title":"Aggregation of alpha\u2010synuclein\/NACP in the neuronal and glial cells in diffuse Lewy body disease: a survey of six patients","volume":"19","author":"Piao YS","year":"2000","journal-title":"Clin Neuropathol"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/61.6.547"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.67"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.20604","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.20604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:29:41Z","timestamp":1760956181000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.20604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7,20]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["10.1002\/mds.20604"],"URL":"https:\/\/doi.org\/10.1002\/mds.20604","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,7,20]]}}}