{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T15:26:07Z","timestamp":1764602767796,"version":"build-2065373602"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,9,13]],"date-time":"2005-09-13T00:00:00Z","timestamp":1126569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to determine the demographic influences on the sensory characteristics (pure visual vs. nonvisual or mixed visual\/nonvisual) of new\u2010onset hallucinations in Parkinson's disease (PD). We utilized 6\u2010year longitudinal interview data from 60 PD patients who had never hallucinated at baseline and reinterviewed them at 6, 18, 48, and 72 months to assess the presence and type of hallucination that developed as the first form of hallucination. We analyzed data by Generalized Estimating Equations methods and by nonparametric tests. Over 6 years, 37 of 60 patients developed hallucinations, and the first hallucinations were pure visual in 18, pure nonvisual in 9, and mixed visual\/nonvisual in 10. At the time of first onset of hallucinations, patients whose hallucinations were nonvisual or mixed were significantly older than those with purely visual hallucinations (mean age, 69.8 \u00b1 8.3 vs. 61.9 \u00b1 10.6; <jats:italic>P<\/jats:italic> = 0.031). PD duration in the two groups, however, was statistically comparable (9.6 \u00b1 4.4 vs. 12.9 \u00b1 8.6 years). Though classically described as visual, hallucinations in PD frequently involve other sensory modalities. Age\u2010related disinhibition may facilitate wider cortical activation in PD and potentiate aberrant signaling that invokes other types of hallucinations besides the classic visual forms. \u00a9 2005 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.20701","type":"journal-article","created":{"date-parts":[[2005,9,13]],"date-time":"2005-09-13T18:19:02Z","timestamp":1126635542000},"page":"267-270","source":"Crossref","is-referenced-by-count":27,"title":["Age\u2010related influences on the clinical characteristics of new\u2010onset hallucinations in Parkinson's disease patients"],"prefix":"10.1002","volume":"21","author":[{"given":"Christopher G.","family":"Goetz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Wuu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Curgian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Leurgans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,8]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1970.00480270003001"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1212\/01.WNL.0000148479.10865.FE","article-title":"Hallucinations and sleep disorders in PD: six year prospective longitudinal study","volume":"64","author":"Goetz CG","year":"2005","journal-title":"Neurology"},{"key":"e_1_2_6_4_2","series-title":"Recent developments in Parkinson's disease","first-page":"153","author":"Fahn S","year":"1987"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.11.2078"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.2307\/2986113"},{"key":"e_1_2_6_7_2","series-title":"Advances in neurology: Parkinson's disease","first-page":"419","author":"Goetz CG","year":"1999"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1996.00550120077019"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-002-0908-9"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000141853.27081.BD"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.58.2.209"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.8.1280"},{"issue":"8","key":"e_1_2_6_13_2","first-page":"S26","article-title":"Serotonin transporter gene polymorphisms and hallucinations in Parkinson's disease","volume":"56","author":"Goldman JG","year":"2004","journal-title":"Ann Neurol"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.20701","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.20701","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:52:16Z","timestamp":1760950336000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.20701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["10.1002\/mds.20701"],"URL":"https:\/\/doi.org\/10.1002\/mds.20701","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"type":"print","value":"0885-3185"},{"type":"electronic","value":"1531-8257"}],"subject":[],"published":{"date-parts":[[2006,2]]}}}