{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T19:54:14Z","timestamp":1770839654617,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2006,6,13]],"date-time":"2006-06-13T00:00:00Z","timestamp":1150156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Berlin Neuroscience Imaging Center","award":["BMBF 01GO0201"],"award-info":[{"award-number":["BMBF 01GO0201"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Alterations in presynaptic and postsynaptic dopaminergic system and cerebral glucose metabolism in corticobasal degeneration (CBD) were assessed to evaluate the potential usefulness of different imaging methods for CBD. <jats:sup>123<\/jats:sup>I\u2010FP\u2010CIT\/<jats:sup>123<\/jats:sup>I\u2010\u03b2\u2010CIT SPECT and <jats:sup>123<\/jats:sup>I\u2010IBZM SPECT as well as <jats:sup>18<\/jats:sup>F\u2010FDG PET were performed in eight CBD patients. Decreased presynaptic dopamine transporter binding was found in all CBD patients while D2 receptor binding was reduced in only one patient. <jats:sup>18<\/jats:sup>F\u2010FDG PET displayed a contralateral hypometabolism in cortical and subcortical areas in seven out of eight patients. Our results demonstrate that glucose metabolism and DAT are reduced, while D2 receptors may be frequently preserved in CBD. \u00a9 2006 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21004","type":"journal-article","created":{"date-parts":[[2006,6,13]],"date-time":"2006-06-13T12:32:23Z","timestamp":1150201943000},"page":"1724-1727","source":"Crossref","is-referenced-by-count":77,"title":["Dopamine transporters, D2 receptors, and glucose metabolism in corticobasal degeneration"],"prefix":"10.1002","volume":"21","author":[{"given":"Stefanie","family":"Klaffke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea A.","family":"Kuhn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michail","family":"Plotkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Amthauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Harnack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Felix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Kupsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,6,13]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1993.00540050063017"},{"key":"e_1_2_6_3_2","first-page":"667","article-title":"Combined 123I\u2010FP\u2010CIT and 123I\u2010IBZM SPECT for the diagnosis of parkinsonian syndromes: study on 72 patients","volume":"211","author":"Plotkin M","year":"2005","journal-title":"J Neural Transm"},{"key":"e_1_2_6_4_2","first-page":"17","article-title":"123I\u2010iodobenzamide\u2010SPECT in 83 patients with de novo parkinsonism","volume":"43","author":"Schwarz J","year":"1993","journal-title":"Neurology"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(04)00936-6"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000149403.14458.7F"},{"key":"e_1_2_6_7_2","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1055\/s-0038-1625189","article-title":"Use of statistical parametric mapping of 18F\u2010FDG\u2010PET in frontal lobe epilepsy","volume":"42","author":"Plotkin M","year":"2003","journal-title":"Nuklearmedizin"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1789.2001.00403.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000117090"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870130107"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/112.5.1171"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-003-0711-4"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.54.10.856"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(02)00102-8"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2005.03.057"},{"key":"e_1_2_6_16_2","first-page":"1029","article-title":"Corticobasal degeneration: an autopsy case clinically diagnosed as progressive supranuclear palsy","volume":"54","author":"Shiozawa M","year":"2000","journal-title":"Clin Neuropathol"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21004","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21004","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:27:45Z","timestamp":1760966865000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.21004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,13]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1002\/mds.21004"],"URL":"https:\/\/doi.org\/10.1002\/mds.21004","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,13]]}}}