{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:50:37Z","timestamp":1786978237109,"version":"build-2736575974"},"reference-count":7,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2006,10,6]],"date-time":"2006-10-06T00:00:00Z","timestamp":1160092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A 53\u2010year\u2010old woman underwent several ischemic stroke\u2010like episodes and later developed incomplete, bilateral ophthalmoplegia, left vision deterioration, and bilateral tremor. The clinical course, laboratory data, and muscle histology led to a diagnosis of mitochondrial encephalomyopathy. No other etiology could be identified in the background of her disabling bilateral postural\u2013kinetic tremor. As this tremor did not respond to pharmacological therapy, left thalamotomy and subsequently right thalamic deep brain stimulator (DBS) implantation were performed, which resulted in an excellent clinical outcome. The Fahn\u2013Tolosa\u2013Marin Tremor Rating Scale improved from 110 to 11 points. This case suggests that the rare tremor caused by mitochondrial encephalopathy may be treated long\u2010term with either thalamotomy or thalamic DBS implantation. \u00a9 2006 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21128","type":"journal-article","created":{"date-parts":[[2006,10,6]],"date-time":"2006-10-06T16:45:56Z","timestamp":1160153156000},"page":"2227-2230","source":"Crossref","is-referenced-by-count":12,"title":["Neurosurgical treatment of tremor in mitochondrial encephalopathy"],"prefix":"10.1002","volume":"21","author":[{"given":"Norbert","family":"Kovacs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Endre","family":"Pal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istvan","family":"Balas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jozsef","family":"Janszky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferenc","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajnalka","family":"Merkli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,10,6]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1351-5101.2003.00728.x"},{"key":"e_1_2_8_3_2","first-page":"463","article-title":"Mitochondrial encephalomyopathy of late presentation with progressive ophthalmoplegia, tremor and diffuse leukoencephalopathy","volume":"14","author":"Franco E","year":"1999","journal-title":"Neurologia"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006823818118"},{"key":"e_1_2_8_5_2","first-page":"225","volume-title":"Parkinson's Disease and Movement Disorders","author":"Fahn S","year":"1998"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/088307380001500110"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1024489218004"},{"key":"e_1_2_8_8_2","first-page":"193","article-title":"Mitochondrial encephalomyopathy of mixed MELAS type","volume":"34","author":"Bertrand E","year":"1996","journal-title":"Folia Neuropathol"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21128","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:42:22Z","timestamp":1760967742000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.21128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,6]]},"references-count":7,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1002\/mds.21128"],"URL":"https:\/\/doi.org\/10.1002\/mds.21128","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,6]]}}}