{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T11:45:50Z","timestamp":1791027950927,"version":"4.1.0"},"reference-count":7,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2006,10,31]],"date-time":"2006-10-31T00:00:00Z","timestamp":1162252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pantothenate kinase\u2010associated neurodegeneration (PKAN) is a rare autosomal recessive disorder with onset in childhood and rapid progression. There is no causative and insufficient symptomatic drug therapy. Deep brain stimulation (DBS) of the internal pallidum (GPi) has been reported to improve motor function. Most case reports, however, are limited to short observational periods. The impact of DBS on the progression and life expectancy in PKAN is unknown. We present a 5\u2010year outcome and video documentation of bilateral GPi\u2010DBS of an adolescent patient suffering from genetically defined PKAN. \u00a9 2006 Movement Disorder Society<\/jats:p>","DOI":"10.1002\/mds.21166","type":"journal-article","created":{"date-parts":[[2006,10,31]],"date-time":"2006-10-31T17:27:43Z","timestamp":1162315663000},"page":"2255-2257","source":"Crossref","is-referenced-by-count":74,"title":["Long\u2010term benefit to pallidal deep brain stimulation in a case of dystonia secondary to pantothenate kinase\u2010associated neurodegeneration"],"prefix":"10.1002","volume":"21","author":[{"given":"Martin","family":"Krause","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Fogel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Tronnier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Pohle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstanze","family":"H\u00f6rtnagel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ute","family":"Thyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Volkmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,10,31]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000143331.86101.5E"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.1.73"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150170116"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2004.100.4.0706"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20457"},{"key":"e_1_2_4_7_2","first-page":"309","article-title":"Off\u2010period dystonia in Parkinson's disease but not generalized dystonia is improved by high\u2010frequency stimulation of the subthalamic nucleus","volume":"94","author":"Detante O","year":"2004","journal-title":"Adv Neurol"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10377"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.21166","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.21166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:42:17Z","timestamp":1760967737000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.21166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,31]]},"references-count":7,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1002\/mds.21166"],"URL":"https:\/\/doi.org\/10.1002\/mds.21166","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"value":"0885-3185","type":"print"},{"value":"1531-8257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,31]]}}}